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M0880

Sigma-Aldrich

Ethyl methanesulfonate

liquid

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Synonym(s):
Ethyl mesylate, Methanesulfonic acid ethyl ester
Linear Formula:
CH3SO3CH2CH3
CAS Number:
Molecular Weight:
124.16
Beilstein:
773969
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.25

form

liquid

Quality Level

refractive index

n20/D 1.418 (lit.)

bp

85-86 °C/10 mmHg (lit.)

density

1.206 g/mL at 20 °C

SMILES string

CCOS(C)(=O)=O

InChI

1S/C3H8O3S/c1-3-6-7(2,4)5/h3H2,1-2H3

InChI key

PLUBXMRUUVWRLT-UHFFFAOYSA-N

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This Item
729458.20774129925
Ethyl methanesulfonate liquid

Sigma-Aldrich

M0880

Ethyl methanesulfonate

Ethyl methanesulfonate certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Supelco

72945

Ethyl methanesulfonate

refractive index

n20/D 1.418 (lit.)

refractive index

n20/D 1.418 (lit.)

refractive index

-

refractive index

n20/D 1.414 (lit.)

bp

85-86 °C/10 mmHg (lit.)

bp

85-86 °C/10 mmHg (lit.)

bp

213-214 °C/1013 hPa

bp

202-203 °C (lit.)

density

1.206 g/mL at 20 °C

density

1.206 g/mL at 20 °C

density

1.206 g/cm3 at 20 °C

density

1.3 g/mL at 25 °C (lit.)

Application

Ethyl methanesulfonate had been used for inducing mutation in mouse embryonic fibroblasts, yeast human embryonic kidney cell lines and human lymphocytes.

Biochem/physiol Actions

Ethyl methanesulfonate is a DNA ethylating agent, mutagenic to plants and animals and carcinogenic in mammals. It has been used as a model alkylating agent in studies of DNA repair processes. EMS induces base substitutions of guanine-cytosine (G/C) to adenine-thymine (A/T). EMS also generates point mutations and single nucleotide polymorphisms in genomes. EMS is potential chemical mutagen used for inducing mutation in rice, wheat and Arabidopsis thaliana.

Pictograms

Exclamation markHealth hazard

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Oral - Carc. 1B - Eye Irrit. 2 - Muta. 1B - Repr. 2 - Skin Irrit. 2 - Skin Sens. 1

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

212.0 °F

Flash Point(C)

100 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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