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M3449

Sigma-Aldrich

Mephedrone hydrochloride

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Synonym(s):
4-Methylmethcathinone hydrochloride
Empirical Formula (Hill Notation):
C11H15NO·HCl
CAS Number:
Molecular Weight:
213.70
MDL number:
PubChem Substance ID:
NACRES:
NA.77

Assay

≥98% (HPLC)

form

powder

drug control

USDEA Schedule I; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IIA (Portugal)

color

white to off-white

solubility

DMSO: >20 mg/mL

storage temp.

room temp

SMILES string

Cl.CNC(C)C(=O)c1ccc(C)cc1

InChI

1S/C11H15NO.ClH/c1-8-4-6-10(7-5-8)11(13)9(2)12-3;/h4-7,9,12H,1-3H3;1H

InChI key

DLQZFTUKJGRPLZ-UHFFFAOYSA-N

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This Item
SML1444SML0460PZ0264
form

powder

form

powder

form

powder

form

powder

drug control

USDEA Schedule I; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IIA (Portugal)

drug control

-

drug control

-

drug control

-

color

white to off-white

color

white to beige

color

white to beige

color

white to beige

solubility

DMSO: >20 mg/mL

solubility

H2O: 20 mg/mL, clear

solubility

H2O: 5 mg/mL (clear solution)

solubility

DMSO: 5 mg/mL, clear (warmed)

storage temp.

room temp

storage temp.

room temp

storage temp.

room temp

storage temp.

room temp

Biochem/physiol Actions

Mephedrone is an inhibitor of monoamine transporter present in the brain and periphery. Mephedrone bears a chiral center and can be found in two enantiomers R-mephedrone and S-mephedrone. Its racemic form is often used as a drug. Mephedrone in rats is known to cause high blood pressure and heart rate, as well as stimulates locomotor hyperactivity. Human trail reveal that mephedrone has the ability to induce euphoria and pleasure.
Mephedrone is a synthetic stimulant, an analog of Cathinone and Methamphetamine.

Features and Benefits

This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Neuropharmacology, 318-318 (2017)

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