M5379
L-Methionine sulfoximine
suitable for cell culture
Synonym(s):
L-S-(3-Amino-3-carboxypropyl)-S-methylsulfoximine
About This Item
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Quality Level
technique(s)
cell based assay: suitable
cell culture | mammalian: suitable
mp
>210 °C (dec.) (lit.)
suitability
suitable for molecular biology
SMILES string
CS(=N)(=O)CC[C@H](N)C(O)=O
InChI
1S/C5H12N2O3S/c1-11(7,10)3-2-4(6)5(8)9/h4,7H,2-3,6H2,1H3,(H,8,9)/t4-,11?/m0/s1
InChI key
SXTAYKAGBXMACB-DPVSGNNYSA-N
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Application
Use of high levels of MSX can enhance productivity and production stability in multiple recombinant GS CHO cell lines and GS–CHOK1SV cell lines without compromising product quality. These findings have important implications for improving the efficiency and reliability of industrial cell culture processes used in the production of biologics.
MSX, a potent convulsant, has shown a specific and significant impact on glutamine dynamics in primary cortical astrocyte cultures. This makes it a valuable compound for studying and modulating glutamine-related processes in cell culture.
Biochem/physiol Actions
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Protocols
LC/MS Analysis of L-Methionine Sulfoximine and Sulfone on Ascentis® Express OH5
Separation of L-Methionine sulfone; L-Methionine sulfoximine; L-Methionine sulfoxide
Chromatograms
application for HPLCapplication for HPLCOur team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
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