M9411

Myristicin from parsley leaf oil

≥85% (HPLC), oil

• Synonym(s): 4-Methoxy-6-(2-propenyl)-1,3-benzodioxole
• Empirical Formula (Hill Notation): C₁₁H₁₂O₃
• CAS Number: 607-91-0
• Molecular Weight: 192.21
• EC Number: 210-146-9
• MDL number: MFCD00133549
• UNSPSC Code: 12352205
• PubChem Substance ID: 24897334
• NACRES: NA.77

Properties

• Quality Level: 200
• assay: ≥85% (HPLC)
• form: oil
• color: clear light yellow
• application(s): metabolomics; vitamins, nutraceuticals, and natural products
• storage temp.: 2-8°C
• SMILES string: COc1cc(CC=C)cc2OCOc12
• InChI: 1S/C11H12O3/c1-3-4-8-5-9(12-2)11-10(6-8)13-7-14-11/h3,5-6H,1,4,7H2,2H3
• InChI key: BNWJOHGLIBDBOB-UHFFFAOYSA-N

Description

General description

Myristicin, a phenylpropene, is an essential oil component.[1] It has anticholinergic and psychotropic activities.[2] Myristicin blocks cytochrome P450 monooxygenases, which detoxifies furanocoumarins.[1] It functions as a serotonin receptor agonist and hallucinogenic agent.[2] Myristicin stimulates glutathione S-transferase activity and might function as a chemopreventive agent.[3] It acts as a precursor for the metabolite 3,4- methylenedioxymethamphetamine (MDMA).[4]

Application

Myristicin from parsley leaf oil has been used to study competitive and uncompetitive inhibition of ACP (acid phosphatase) and ALP (alkaline phosphatase).[5]

Biochem/physiol Actions

Myristicin induces the expression of glutathione S-transferase and cytochrome P450 (Cyp1a-1) in liver cells. May enhance detoxification of carcinogenic substances.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H336
• pcodes: P261 - P271 - P304 + P340 + P312 - P403 + P233 - P405 - P501
• Hazard Classifications: STOT SE 3
• target_organs: Central nervous system
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type ABEK (EN14387) respirator filter