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M9659

Sigma-Aldrich

4-Methylumbelliferyl N-acetyl-β-D-galactosaminide

≥98% (HPLC), powder

Synonym(s):

4-Methylumbelliferyl 2-acetamido-2-deoxy-β-D-galactopyranoside

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About This Item

Empirical Formula (Hill Notation):
C18H21NO8
CAS Number:
36476-29-6
Molecular Weight:
379.36
EC Number:
253-052-3
MDL number:
MFCD00067658
UNSPSC Code:
12352204
PubChem Substance ID:
24897348
NACRES:
NA.32

product name

4-Methylumbelliferyl N-acetyl-β-D-galactosaminide, ≥98% (HPLC)

Quality Level

200

assay

≥98% (HPLC)

form

powder

solubility

pyridine: 50 mg/mL, clear, colorless to faintly yellow

storage temp.

−20°C

SMILES string

CC(=O)NC1C(O)C(O)C(CO)OC1Oc2ccc3C(C)=CC(=O)Oc3c2

InChI

1S/C18H21NO8/c1-8-5-14(22)26-12-6-10(3-4-11(8)12)25-18-15(19-9(2)21)17(24)16(23)13(7-20)27-18/h3-6,13,15-18,20,23-24H,7H2,1-2H3,(H,19,21)

InChI key

QCTHLCFVVACBSA-UHFFFAOYSA-N

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Application

4-Methylumbelliferyl N-acetyl-β-ᴅ-galactosaminide has been used as a substrate in the O-GlcNAcase assay.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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M F Simpanya
Journal of medical microbiology, 43(3), 230-233 (1995-09-01)
The 4-methylumbelliferyl-N-acetyl-beta-D-galactosaminide (UAG) test was evaluated in parallel with chlamydospore (CHL) and germ-tube (GT) tests for the identification of Candida spp. The UAG test gave 86.6% correct identification of C. albicans and C. tropicalis. Non-C. albicans and non-C. tropicalis yeasts
Reiko Tanaka et al.
Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology, 46(2), 125-128 (2005-05-03)
To evaluate a newly developed identification kit, the RID Zyme CAS test for Candida albicans, 1136 C. albicans and 403 non-albicans Candida strains were tested. Distinction of medically important non-albicans strains, with the exception of C. dubliniensis, was obtained. These
M T Dalton et al.
Diagnostic microbiology and infectious disease, 12(6), 521-523 (1989-11-01)
Rapid identification of Candida albicans is performed mainly by the germ-tube test. However, recent reports have suggested that up to 5% of C. albicans species can give false negative results. We describe the use of 4-Methylumbelliferyl N-acetyl-beta-D-galactosaminide (4-MAG) conjugate as
Zhiming Shen et al.
Artificial cells, nanomedicine, and biotechnology, 48(1), 656-663 (2020-02-20)
Smoking is an important factor in the pathogenesis of chronic obstructive pulmonary disease (COPD), which is commonly characterised by cellular senescence and inflammation. Recently, miR-200b has emerged as an important target to cure lung disease; however, the function of miR-200b
H De Boeck et al.
The Journal of biological chemistry, 259(11), 7067-7074 (1984-06-10)
The number of carbohydrate-binding sites of the GalNAc-specific lectin is four per tetramer. The binding parameters of N-acetyl-D-galactosamine and methyl-N-acetyl-alpha-D- galactosaminide , were determined by titrating the perturbation in the absorption spectrum of the protein. For D-galactosides, it was necessary

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