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N6125

Sigma-Aldrich

Naphthol AS-TR phosphate disodium salt

fluorogenic, ≥99% (HPLC), powder

Synonym(s):

NASTRp disodium salt

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About This Item

Empirical Formula (Hill Notation):
C18H13ClNNa2O5P
CAS Number:
4264-93-1
Molecular Weight:
435.71
MDL number:
MFCD00069550
UNSPSC Code:
12352204
PubChem Substance ID:
24897766
NACRES:
NA.83

product name

Naphthol AS-TR phosphate disodium salt, ≥99% (HPLC), Bulk package

Quality Level

300

assay

≥99% (HPLC)

form

powder

solubility

water: 50 mg/mL, clear, colorless to faintly yellow

storage temp.

−20°C

SMILES string

[Na+].[Na+].Cc1cc(Cl)ccc1NC(=O)c2cc3ccccc3cc2OP([O-])([O-])=O

InChI

1S/C18H15ClNO5P.2Na/c1-11-8-14(19)6-7-16(11)20-18(21)15-9-12-4-2-3-5-13(12)10-17(15)25-26(22,23)24;;/h2-10H,1H3,(H,20,21)(H2,22,23,24);;/q;2*+1/p-2

InChI key

TYCHZTPSWMGRRI-UHFFFAOYSA-L

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Application

Substrate for the histochemical demonstration of acid and alkaline phosphatase.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Adéla Kratochvílová et al.
Scientific reports, 10(1), 7489-7489 (2020-05-06)
Caspases are proteases traditionally associated with inflammation and cell death. Recently, they have also been shown to modulate cell proliferation and differentiation. The aim of the current research was to search for osteogenic molecules affected by caspase inhibition and to specify
Claire Chevalier et al.
STAR protocols, 2(2), 100452-100452 (2021-04-30)
Mesenchymal-derived osteoblasts play a key role in bone formation via synthesis and mineralization of the bone and bone remodeling. Osteoclasts are multinucleated cells of hematopoietic origin with a role in bone resorption. Here, we describe a protocol for generating primary
Barbora Vesela et al.
Frontiers in cell and developmental biology, 8, 589136-589136 (2020-11-13)
Caspases are evolutionary conserved proteases traditionally known as participating in apoptosis and inflammation but recently discovered also in association with other processes such as proliferation or differentiation. This investigation focuses on caspase-12, ranked among inflammatory caspases but displaying other, not
Eva Svandova et al.
Journal of anatomy, 235(2), 256-261 (2019-05-31)
FASL (CD178) is known for its role in triggering apoptosis, mostly in relation with immune cells but additional functions have been reported more recently, including those in bone development. Examination of postnatal FasL-deficient mice (gld) showed an increased bone deposition
Claire Chevalier et al.
Cell metabolism, 32(4), 575-590 (2020-09-12)
Osteoporosis is the most prevalent metabolic bone disease, characterized by low bone mass and microarchitectural deterioration. Here, we show that warmth exposure (34°C) protects against ovariectomy-induced bone loss by increasing trabecular bone volume, connectivity density, and thickness, leading to improved
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