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N6877

Sigma-Aldrich

L-Norleucine

≥98% (TLC)

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Synonym(s):
(S)-(+)-2-Aminohexanoic acid, (S)-2-Aminocaproic acid
Linear Formula:
CH3(CH2)3CH(NH2)CO2H
CAS Number:
327-57-1
Molecular Weight:
131.17
Beilstein/REAXYS Number:
1721750
EC Number:
206-321-4
MDL number:
MFCD00064423
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
24897796
NACRES:
NA.26

Quality Level

200

assay

≥98% (TLC)

form

powder

color

white

mp

>300 °C (lit.)

application(s)

detection

SMILES string

CCCC[C@H](N)C(O)=O

InChI

1S/C6H13NO2/c1-2-3-4-5(7)6(8)9/h5H,2-4,7H2,1H3,(H,8,9)/t5-/m0/s1

InChI key

LRQKBLKVPFOOQJ-YFKPBYRVSA-N

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Related Categories

Application


  • l-norleucine on high glucose-induced insulin sensitivity and mitochondrial function in skeletal muscle cells. This study explores the beneficial effects of L-Norleucine on insulin sensitivity and mitochondrial function, underlining its potential in metabolic pathway research and its application in managing diabetes through targeted amino acid therapy (Ding et al., 2024).

Biochem/physiol Actions

L-Norleucine is a synthetic amino acid commonly used as an internal standard.

Other Notes

Non-essential amino acid.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H317

Hazard Classifications

Skin Sens. 1

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Following the studies of urea denaturation of β-hairpins using molecular dynamics, in this paper, molecular dynamics simulations of two peptides, a 35 residue three helix bundle villin headpiece protein HP-35 and its doubly norleucine-substituent mutant (Lys24Nle/Lys29Nle) HP-35 NleNle, were undertaken
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