N7787
NS3694
≥98%, powder
Synonym(s):
4-Chloro-2-[3-(3-trifluoromethyl-phenyl)-ureido]benzoic acid
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Empirical Formula (Hill Notation):
C15H10ClF3N2O3
CAS Number:
Molecular Weight:
358.70
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
Recommended Products
assay
≥98%
form
powder
solubility
DMSO: soluble 22 mg/mL
H2O: insoluble <5 mg/mL
storage temp.
2-8°C
SMILES string
OC(=O)c1ccc(Cl)cc1NC(=O)Nc2cccc(c2)C(F)(F)F
InChI
1S/C15H10ClF3N2O3/c16-9-4-5-11(13(22)23)12(7-9)21-14(24)20-10-3-1-2-8(6-10)15(17,18)19/h1-7H,(H,22,23)(H2,20,21,24)
InChI key
GNCZTZCPXFDPLI-UHFFFAOYSA-N
Gene Information
human ... GRIK1(2897)
Application
NS3694 may be used as an apoptosis inhibitor to study the relationship between the cellular mechanisms controlled by amputation-induced myeloid lineage activity.
Biochem/physiol Actions
NS3694 can prevent the active apoptosome complex formation.
NS3694 is an Inhibitor of apoptosome formation.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Cindy X Kha et al.
Experimental eye research, 169, 38-47 (2018-01-23)
Vertebrate eye development is complex and requires early interactions between neuroectoderm and surface ectoderm during embryogenesis. In the African clawed frog, Xenopus laevis, individual eye tissues such as the retina and lens can undergo regeneration. However, it has been reported
Jovany J Franco et al.
Molecular biology of the cell, 30(16), 1890-1899 (2019-02-21)
Epithelial wound healing requires a complex orchestration of cellular rearrangements and movements to restore tissue architecture and function after injury. While it is well known that mechanical forces can affect tissue morphogenesis and patterning, how the biophysical cues generated after
Developmental dependence for functional eye regrowth in Xenopus laevis.
Cindy X Kha et al.
Neural regeneration research, 13(10), 1735-1737 (2018-08-24)
Ulrik Lademann et al.
Molecular and cellular biology, 23(21), 7829-7837 (2003-10-16)
The release of mitochondrial proapoptotic proteins into the cytosol is the key event in apoptosis signaling, leading to the activation of caspases. Once in the cytosol, cytochrome c triggers the formation of a caspase-activating protein complex called the apoptosome, whereas
Can Aztekin et al.
Development (Cambridge, England), 147(3) (2020-01-29)
Regeneration-competent vertebrates are considered to suppress inflammation faster than non-regenerating ones. Hence, understanding the cellular mechanisms affected by immune cells and inflammation can help develop strategies to promote tissue repair and regeneration. Here, we took advantage of naturally occurring tail
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service