P1614
Protein kinase Cζ pseudosubstrate, myristoyl trifluoroacetate salt
≥90% (HPLC)
Synonym(s):
PKC Zeta Pseudosubstrate Inhibitory peptide, ZIP
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About This Item
Recommended Products
Quality Level
assay
≥90% (HPLC)
form
powder
mol wt
calculated mol wt 1928
solubility
H2O: soluble
storage temp.
−20°C
Amino Acid Sequence
Myr-Ser-Ile-Tyr-Arg-Arg-Gly-Ala-Arg--Arg-Trp-Arg-Lys-Leu
Biochem/physiol Actions
Cell permeable protein kinase C (PKC) ζ inhibitor.
Features and Benefits
This compound is featured on the PKC page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Certificates of Analysis (COA)
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P M Dang et al.
Journal of immunology (Baltimore, Md. : 1950), 166(2), 1206-1213 (2001-01-06)
Generation of superoxide anion by the multiprotein complex NADPH phagocyte oxidase is accompanied by extensive phosphorylation of its 47-kDa protein component, p47(phox), a major cytosolic component of this oxidase. Protein kinase C zeta (PKC zeta), an atypical PKC isoform expressed
Miguel Salinas-Saavedra et al.
eLife, 7 (2018-08-01)
In triploblastic animals, Par-proteins regulate cell-polarity and adherens junctions of both ectodermal and endodermal epithelia. But, in embryos of the diploblastic cnidarian Nematostella vectensis, Par-proteins are degraded in all cells in the bifunctional gastrodermal epithelium. Using immunohistochemistry, CRISPR/Cas9 mutagenesis, and
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