P2850
Phosphatase Inhibitor Cocktail 1
DMSO solution, mixture of inhibitors
Sign Into View Organizational & Contract Pricing
All Photos(2)
About This Item
Recommended Products
product name
Phosphatase Inhibitor Cocktail 1, DMSO solution
form
DMSO solution
Quality Level
shipped in
wet ice
storage temp.
2-8°C
General description
Phosphatase Inhibitor Cocktail 1 includes a mixture of inhibitors that will inhibit the L-isozymes of alkaline phosphatase as well as serine/threonine protein phosphatases such as PP1 and PP2A. This product contains microcystinLR, cantharidin, and (−)-p-bromotetramisole. Phosphatase Inhibitor Cocktail 1 has been replaced with P0044.
Application
Phosphatase Inhibitor Cocktail 1 has been used in nuclear protein isolation and electrophoretic mobility shift assay (EMSA) for catenin activation. It has also been used in western blot analysis.
Biochem/physiol Actions
Phosphatases are active regulators of a number of important biological processes. Inhibition of phosphatases by small molecules is useful to study its biological role.
Quantity
Recommended usage is a 100-fold dilution.
Analysis Note
Tested on cell extracts from animal tissues such as bovine liver, human placenta, and rabbit muscle, as well as on extracts from A431 and Jurkat cell lines.
wgk_germany
WGK 1
flash_point_f
188.6 °F
flash_point_c
87 °C
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Customers Also Viewed
Mucosal immunology, 10(6), 1553-1568 (2017-04-13)
Virulent Mycobacterium tuberculosis (Mtb) triggers necrosis in host Mϕ, which is essential for successful pathogenesis in tuberculosis. Here we demonstrate that necrosis of Mtb-infected Mϕ is dependent on the action of the cytosolic Receptor Interacting Protein Kinase 3 (RIPK3) and
Class III β-tubulin expression and in vitro resistance to microtubule targeting agents.
British Journal of Cancer, 102(2), 316-316 (2010)
Discovery of protein phosphatase inhibitor classes by biology-oriented synthesis.
Proceedings of the National Academy of Sciences of the USA, 103(28), 10606-10611 (2006)
Larger therapeutic window for steroid versus VEGF-A inhibitor in inflammatory angiogenesis: surprisingly similar impact on leukocyte infiltration.
Investigative Ophthalmology & Visual Science, 53(7), 3296-3302 (2012)
Aberrant Wnt/β-catenin signaling in pancreatic adenocarcinoma.
Neoplasia, 8(4), 279-289 (2006)
Articles
The use of phosphatase inhibitors is critical for all types of phosphorylation studies. Compare phosphatase inhibitor cocktails to select the best one for your research.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service