P3513
Poly-L-lysine, succinylated
mol wt >50,000
Synonym(s):
Modified Lysine Copolymer
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About This Item
Recommended Products
form
powder or solid
Quality Level
mol wt
>50,000
color
white to faint yellow
application(s)
cell analysis
storage temp.
−20°C
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Application
Succinylated poly-L-lysine has been used to bind (Gly)3-Arg-bradykinin to study its hydrolysis by brain endopeptidases and pancreatic proteinases.
Biochem/physiol Actions
Poly-L-lysine is a cationic polymer. It is mainly used for immobilizing cells to glass substrates or negatively charged substrates.
An intermediate for coupling proteins to poly-L-lysine.
Analysis Note
Molecular weight based on precursor poly-L-lysine viscosity. Also assayed by MALLS.
Other Notes
For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Certificates of Analysis (COA)
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Effects of poly(L-lysine) substrates on attached Escherichia coli bacteria.
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Avidin-coupled monoclonal antibody MX35 (avidin-MX35) and astatine-211-labeled, biotinylated, succinylated poly-l-lysine ((211)At-B-PL(suc)) were administered in mice to assess potential efficacy as an intraperitoneal (i.p.) therapy for microscopic tumors. We aimed to establish a timeline for pretargeted radioimmunotherapy using these substances, and
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