Skip to Content
MilliporeSigma

P3683

Paraplast Plus®

for tissue embedding

Synonym(s):

Paraplast Plus® embedding media, Paraffin – polyisobutylene mixture

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

CAS Number:
UNSPSC Code:
12171500
EC Number:
232-315-6
NACRES:
NA.47
MDL number:
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist


Quality Level

form

solid

mp

56-57 °C (lit.)

application(s)

hematology
histology

storage temp.

room temp

General description

Paraplast Plus® is a refined mixture of highly purified paraffin containing complex elastomer of regulated molecular weights plus a small percentage of dimethyl sulfoxide (DMSO) for fast tissue penetration. It produces minimal tissue compression and wrinkle-free sections and cuts to 4 μm thickness with excellent ribbon continuity.
Paraplast® tissue embedding media are made from highly purified wax combined with plastic polymers for tensile strength and elasticity. Paraplast Plus® provides rapid infiltration during processing as well as great compression resistance during sectioning for preserved morphology and thin, distortion-free sections.
Our range of Paraplast products improve the elasticity of brittle, difficult-to-cut tissues making it easier to produce excellent, wrinkle-free sections.

Application

Paraplast Plus® is recommended for large specimens and tissue that commonly presents infiltration problems. It has been used:
  • in the examination of vertebral specimens of Malacoraja senta.
  • in the identification and expression analysis of PIN genes in rice.
  • in the study of glucose transport mechanisms in uterine tissues during pregnancy.
  • to embed Bouin′s fixed carp tissues, rat ventral prostatic fragments, and common bean (Phaseolus vulgaris L.) nodules.

Features and Benefits

  • Produces minimal tissue compression and wrinkle-free sections, and cuts to 4 μm thickness with excellent ribbon continuity.
  • 0.8% DMSO enhances ease of infiltration and sectioning for tissues difficult to process with regular Paraplast.
  • Higher melt viscosity and lower permeability to water vapor creates better adhesion and a more pliable, flexible film.
  • Optimal infiltration and embedding for high-quality sections.
  • Great compression resistance and ribbon continuity.
  • Remarkable morphology preservation and distortion-free sections.

Legal Information

Paraplast is a registered trademark of Leica Biosystems
Paraplast Plus is a registered trademark of Leica Biosystems


Still not finding the right product?

Explore all of our products under Paraplast Plus®


Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library


Related Content

Three-dimensional (3D) printing of biological tissue is rapidly becoming an integral part of tissue engineering.


Nozomu Yoshioka et al.
Disease models & mechanisms, 13(5) (2020-06-03)
Loss-of-function mutations in dystonin (DST) can cause hereditary sensory and autonomic neuropathy type 6 (HSAN-VI) or epidermolysis bullosa simplex (EBS). Recently, DST-related diseases were recognized to be more complex than previously thought because a patient exhibited both neurological and skin
Micro-morphology of common bean (Phaseolus vulgaris L.)
nodules undergoing senescence
Fabia'n Ferna'ndez-Luquen?o ? L.
Acta Physiologiae Plantarum / Polish Academy of Sciences, Committee of Plant Physiology Genetics and Breeding (2008)
Identification and expression analysis of PIN genes in rice
Miyashita, et al.
Plant Science, 178(5) (2010)



Global Trade Item Number

SKUGTIN
P3683-1KG04061835573875