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Key Documents

P3558

Sigma-Aldrich

Paraplast®

for tissue embedding

Synonym(s):

Paraplast® embedding media, Paraffin – polyisobutylene mixture

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12171500
NACRES:
NA.47

form

solid

mp

56-57 °C (lit.)
56-57 °C

application(s)

hematology
histology

storage temp.

room temp

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General description

Paraplast® is a paraffin–polyisobutylene mixture for tissue embedding and infiltration. It is a refined combination of highly purified paraffin-containing plastic polymers of regulated molecular weights. It produces minimal tissue compression and wrinkle-free sections and cuts to 4 μm thickness with excellent ribbon continuity.
Paraplast® tissue embedding media are made from highly purified wax combined with plastic polymers for tensile strength and elasticity. Paraplast provides rapid infiltration during processing as well as great compression resistance during sectioning for preserved morphology and thin, distortion-free sections.
Our range of Paraplast products improve the elasticity of brittle, difficult-to-cut tissues making it easier to produce excellent, wrinkle-free sections.

Application

Paraplast® has been used for tissue embedding and in the following applications:
  • to screen major groups of vertebrates for the presence of cardiac smooth muscle and its phylogenetic distribution in terrestrial and aquatic turtles
  • to study the relationship between membrane impedance and dendrite length of hippocampal neurons
  • to compare the regenerative properties of human stem cells of the apical papilla as an alternative to other dental stem cells

Features and Benefits

  • Produces minimal tissue compression and wrinkle-free sections, and cuts to 4 μm thickness with excellent ribbon continuity.
  • Higher melt viscosity and lower permeability to water vapor creates better adhesion and a more pliable, flexible film.
  • Optimal infiltration and embedding for high-quality sections.
  • Great compression resistance and ribbon continuity.
  • Remarkable morphology preservation and distortion-free sections.

Other Notes

Double filtered paraffin wax in pellet form.

Legal Information

Paraplast is a registered trademark of Leica Biosystems

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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