MilliporeSigma
All Photos(1)

Documents

P7556

Sigma-Aldrich

Progesterone-Water Soluble

powder, BioReagent, suitable for cell culture

Sign Into View Organizational & Contract Pricing

Synonym(s):
Progesterone: HBC complex, Progesterone: methyl-β-cyclodextrin complex
MDL number:
PubChem Substance ID:
NACRES:
NA.77

biological source

synthetic (organic)

product line

BioReagent

form

powder

concentration

≥65% (HPLC)

technique(s)

cell culture | mammalian: suitable

solubility

H2O: 25 mg/mL, clear to slightly hazy

shipped in

ambient

storage temp.

room temp

SMILES string

[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)[C@H](CC[C@@]24[H])C(C)=O

InChI

1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1

InChI key

RJKFOVLPORLFTN-LEKSSAKUSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
E4389H0396C4951
product line

BioReagent

product line

BioReagent

product line

BioReagent

product line

BioReagent

form

powder

form

powder

form

crystalline

form

powder

concentration

≥65% (HPLC)

concentration

-

concentration

-

concentration

-

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

solubility

H2O: 25 mg/mL, clear to slightly hazy

solubility

H2O: 25 mg/mL, clear to slightly hazy

solubility

H2O: 400 mg/mL

solubility

H2O: 300 mg/mL

General description

Progesterone is a steroid hormone secreted by the ovaries.

Application

Progesterone-Water Soluble has been used:
  • for in vitro maturation of oocyte complexes
  • as a σ1R antagonist to study its effect on sigma 1 receptor
  • to study its effect on the differentiation of human multipotent mesenchymal stromal cells (hMSCs) in vitro

This product is not recommended for use in binding assays.

Biochem/physiol Actions

Progesterone is a hormone that maintains pregnancy. It is essential for embryo formation, development and survival in almost all mammals. This hormone exhibits its action via progesterone receptor, which is specifically expressed in the endometrial stroma throughout pregnancy. It is known to prevent preterm delivery, when administered intramuscularly. Progesterone also controls gonadotropin secretion, activates sexual behavior and triggers ovarian events leading to ovulation. It stimulates the growth and differentiation of the uterus and prevents uterine contractility.

Packaging

Package size based on progesterone content

Other Notes

Contains approx. 70 mg progesterone per gram; balance methyl-β-cyclodextrin.

related product

Pictograms

Health hazard

Signal Word

Danger

Hazard Statements

Hazard Classifications

Carc. 2 - Lact. - Repr. 1A

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Customers Also Viewed

Slide 1 of 8

1 of 8

Progesterone British Pharmacopoeia (BP) Reference Standard

BP449

Progesterone

Progesterone Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1142

Progesterone

β-Estradiol BioReagent, powder, suitable for cell culture

Sigma-Aldrich

E2758

β-Estradiol

Progesterone VETRANAL®, analytical standard

Supelco

46665

Progesterone

Progesterone Steroid hormone secreted by the corpus luteum during the latter half of the menstrual cycle.

Sigma-Aldrich

5341

Progesterone

Progesterone European Pharmacopoeia (EP) Reference Standard

P3300000

Progesterone

Neurosteroid Hormones Modulate the Differentiation of Adult Human Multipotent Mesenchymal Stromal Cells
Tiftikcioglu BI, et al.
Journal of stem cell research & therapy, 4(9), 2-2 (2012)
Clinical Reproductive Medicine and Surgery, 838, 17-17 (2007)
Adding hormones sequentially could be an effective approach for IVM of dog oocytes
Evecen M, et al.
Theriogenology, 75(9), 1647-1651 (2011)
Ligands exert Biased Activity to regulate Sigma 1 Receptor interactions with cationic TRPA1, TRPV1 and TRPM8 channels
Cortes ME, et al.
Frontiers in Pharmacology, 10(9), 634-634 (2019)
Neonatal progesterone programs adult uterine responses to progesterone and susceptibility to uterine dysfunction
Dhakal P, et al.
Endocrinology, 156(10), 3791-3803 (2015)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service