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P7936

Sigma-Aldrich

Phosphocreatine disodium salt hydrate

≥97%

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Synonym(s):
Creatine phosphate disodium salt, N-(Imino[phosphonoamino]methyl)-N-methylglycine
Linear Formula:
C4H8N3O5PNa2 · x H2O
CAS Number:
Molecular Weight:
255.08 (anhydrous basis)
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.32

Quality Level

assay

≥97%

form

powder

impurities

≤0.02% free creatine

color

white

solubility

water: 50 mg/mL, clear, colorless

storage temp.

−20°C

SMILES string

O.[Na+].[Na+].CN(CC(O)=O)C(=N)NP([O-])([O-])=O

InChI

1S/C4H10N3O5P.2Na.H2O/c1-7(2-3(8)9)4(5)6-13(10,11)12;;;/h2H2,1H3,(H,8,9)(H4,5,6,10,11,12);;;1H2/q;2*+1;/p-2

InChI key

KZVYPOKBYRXZKS-UHFFFAOYSA-L

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This Item
P1937279202380
Phosphocreatine di(tris) salt ≥97% (enzymatic)

P1937

Phosphocreatine di(tris) salt

Sigma-Aldrich

2380

Creatine Phosphate, Disodium Salt

assay

≥97%

assay

≥97% (enzymatic)

assay

≥98.0% (NT)

assay

≥97% (TLC)

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

−20°C

impurities

≤0.02% free creatine

impurities

-

impurities

≤0.6% free creatine

impurities

-

color

white

color

white

color

-

color

white

solubility

water: 50 mg/mL, clear, colorless

solubility

water: 50 mg/mL, clear to very slightly hazy, colorless

solubility

H2O: 0.1 g/mL, clear, colorless

solubility

water: 150 mg/mL

Application

Phosphocreatine disodium salt hydrate has been used:
  • as a component: of Xenopus buffer (XB) buffer to remove the membrane-bound proteins
  • of M5+ buffer to perform polarized total internal reflection fluorescence (polTIRF) experiments
  • of ATP regenerating system for 7-nitro-2-1,3-benzoxadiazol-4-yl phospholipid(NBD-PL) translocation assay

Biochem/physiol Actions

Phosphocreatine disodium salt hydrate is useful to study nasopharyngeal carcinoma cells and induced temporary cardiac arrest. It also evaluate the effects of adenosine A(2A) receptor modulation in the nucleus accumbens on cocaine seeking in rats.
Phosphocreatine is widely known for its quickest form of regeneration using enzyme creatine kinase. It functions as a temporal energy buffer. Phosphocreatine is present in muscle tissues and plays a major role in maintaining energy homeostasis in muscle cells.
Phosphocreatine, a high-energy phosphate reservoir in vertebrate and some invertebrate muscles, provides phosphate for ADP-ATP conversion.

Preparation Note

Prepared enzymatically

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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