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PHG0007

SAFC

MOPS

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Synonym(s):
3-(N-Morpholino)propanesulfonic acid, 4-Morpholinepropanesulfonic acid
Empirical Formula (Hill Notation):
C7H15NO4S
CAS Number:
Molecular Weight:
209.26
Beilstein:
1106776
EC Number:
MDL number:
NACRES:
NA.21

biological source

synthetic

Quality Level

Assay

≥99.5%

form

powder

technique(s)

cell culture | mammalian: suitable

impurities

Endotoxin, microbial, and trace metals; tested

pH

2.5-4 (1 M in H2O)

useful pH range

6.5-7.9

pKa (25 °C)

7.2

λ

1 M in H2O

suitability

suitable for manufacturing use

foreign activity

Cytotoxicity, DNase, NICKase, RNase, and Protease; tested

SMILES string

OS(=O)(=O)CCCN1CCOCC1

InChI

1S/C7H15NO4S/c9-13(10,11)7-1-2-8-3-5-12-6-4-8/h1-7H2,(H,9,10,11)

InChI key

DVLFYONBTKHTER-UHFFFAOYSA-N

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This Item
M3183M516269947
MOPS

SAFC

PHG0007

MOPS

-
MOPS BioPerformance Certified, suitable for cell culture, ≥99.5% (titration)

Sigma-Aldrich

M3183

MOPS

Premium Grade
MOPS BioXtra, ≥99.5% (titration)

Sigma-Aldrich

M5162

MOPS

Premium Grade
MOPS BioUltra, for molecular biology, ≥99.5% (T)

Sigma-Aldrich

69947

MOPS

Premium Grade
form

powder

form

crystalline powder

form

powder

form

powder or crystals

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable, electrophoresis: suitable

technique(s)

-

impurities

Endotoxin, microbial, and trace metals; tested

impurities

endotoxin and TAMC, tested

impurities

Insoluble matter, passes filter test

impurities

DNases, none detected, RNases, none detected, insoluble matter, passes filter test, phosphatases, none detected, proteases, none detected

pH

2.5-4 (1 M in H2O)

pH

2.5-4 (25 °C, 209 g/L)

pH

2.5-4.0 (1 M in H2O)

pH

2.5-4.0 (25 °C, 1 M in H2O)

suitability

suitable for manufacturing use

suitability

-

suitability

-

suitability

-

General description

Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Buffer quality is vital for the success of biopharmaceutical processes, because buffers are indispensable in nearly every production step.

Our broad portfolio of buffer materials manufactured under appropriate controls is tailored to your needs. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.

Application

MOPS is a biological buffer also referred to as a “Propane Sultone” buffer. The pKa of MOPS is 7.01 which make it an ideal candidate for medias and protein based buffer formulations to maintain a stable environment in solution. MOPS is considered to be non-toxic to culture cell lines and provides high-solution clarity.

MOPS is used in cell culture media, biopharmaceutical buffer formulations (both upstream and downstream). MOPS based buffers are used in purification bioprocesses of antibodies, peptides, proteins and blood components.

Legal Information

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

230.0 °F - closed cup

Flash Point(C)

110 °C - closed cup


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Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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