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species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
input
sample type plasma
sample type serum
sample type cell culture supernatant(s)
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.08 ng/mL
standard curve range: 0.082-20 ng/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... APOA1(335)
General description
Apolipoprotein A-1 (APOA1) is a major constituent of high-density lipoprotein (HDL) cholesterol. It aids in reverse cholesterol transport (RCT). In addition, apoA1 is also implicated in the pathways that protect endothelial functions, induce nitric oxide-mediated vasodilatation, and reduce vascular cell adhesion molecule-1 (VCAM-I) expression. APOA1 stimulates proliferation by inhibiting apoptosis. The ApoA enzyme-linked immunosorbent assay (ELISA) kit provides for the quantitative measurement of ApoA1 in cell culture supernatants, plasma, and serum.
The ApoA ELISA kit provides for the Quantitative measurement of ApoA1 in Cell Culture Supernatants, Plasma and Serum.
Application
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
Storage Class
8A - Combustible corrosive hazardous materials
flash_point_f
Not applicable
flash_point_c
Not applicable
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Manja Koch et al.
Journal of lipid research, 58(6), 1196-1203 (2017-04-04)
The presence of apoC-III on HDL impairs HDL's inverse association with coronary heart disease (CHD). Little is known about modifiable factors explaining variation in HDL subspecies defined according to apoC-III. The aim was to investigate cross-sectional associations of anthropometry and
Thomas Lundåsen et al.
PloS one, 15(3), e0229322-e0229322 (2020-03-17)
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Michael A Tortorici et al.
Clinical pharmacology in drug development, 8(5), 628-636 (2018-09-22)
CSL112 (Apolipoprotein A-I [human]) is an intravenous preparation of apolipoprotein A-I (apoA-I), formulated with phosphatidylcholine (PC) and stabilized with sucrose, in development to prevent early recurrent cardiovascular events following acute myocardial infarction (AMI). This phase 1 study was designed to
Jolanta Parada-Turska et al.
Antioxidants (Basel, Switzerland), 9(9) (2020-09-25)
Paraoxonase 1 (PON1) is the high density lipoprotein-associated esterase which inhibits the development of atherosclerosis by metabolizing lipid peroxidation products as well as hydrolyzing proatherogenic metabolite of homocysteine (Hcy), Hcy thiolactone, which otherwise reacts with lysine groups of proteins, thus
Mathilde Mouchiroud et al.
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Nonalcoholic fatty liver disease (NAFLD) prevails in obesity and is linked to several health complications including dyslipidemia and atherosclerosis. How exactly NAFLD induces atherogenic dyslipidemia to promote cardiovascular diseases is still elusive. Here, we identify Tsukushi (TSK) as a hepatokine
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