S0885
Somatostatin
γ-irradiated, powder, BioXtra, suitable for cell culture
Synonym(s):
Growth hormone release inhibiting factor, SRIF, Somatostatin-14, Somatotropin release inhibiting factor
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About This Item
Empirical Formula (Hill Notation):
C76H104N18O19S2
CAS Number:
Molecular Weight:
1637.88
Beilstein/REAXYS Number:
6436064
EC Number:
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.77
biological source:
synthetic (organic)
form:
powder
assay:
≥50%
Recommended Products
biological source
synthetic (organic)
Quality Level
sterility
γ-irradiated
product line
BioXtra
assay
≥50%
form
powder
potency
0.3-50 ng/mL
concentration
≥50% (HPLC)
technique(s)
cell culture | mammalian: suitable
solubility
cell culture medium: 10 mL/vial
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Amino Acid Sequence
Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys
Biochem/physiol Actions
Somatostatin regulates endocrine function and cell proliferation via interaction with G-protein-coupled somatostatin receptors. It exists in two active forms produced by alternative cleavage of a single preproprotein (14 aa and 28 aa forms). Somatosatin inhibits the release of growth hormone; thyroid-stimulating hormone and a range of gastrointestinal hormones: Cholecystokinin (CCK); Enteroglucagon; Gastrin; Gastric inhibitory polypeptide (GIP); Motilin; Secretin; Vasoactive intestinal peptide (VIP).
Physical form
powder-0 °C; stock-frozen in working aliquots, avoid repeated freeze/thaw
Reconstitution
To prepare 2 μg/ml stock solution, add 10 ml sterile culture medium.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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