S4045
Monoclonal Anti-Splicing Factor SC-35 antibody produced in mouse
clone SC-35, ascites fluid
Synonym(s):
Anti-SC-35, Anti-SC35
About This Item
Recommended Products
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
ascites fluid
antibody product type
primary antibodies
clone
SC-35, monoclonal
mol wt
antigen 35 kDa (a doublet)
contains
15 mM sodium azide
species reactivity
frog, Drosophila, newt, rat, human
technique(s)
electron microscopy: suitable
immunocytochemistry: suitable
immunoprecipitation (IP): suitable
indirect ELISA: suitable
indirect immunofluorescence: 1:2,000 using cultured human fibroblasts
isotype
IgG1
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... SFRS2(6427)
rat ... Sfrs2(494445)
General description
The essential non-snRNP splicing factor SC-35 displays a speckled distribution in the nucleus that co-localizes with snRNPs, but unlike snRNPs, SC-35 does not give diffuse nuclear labelling. In the nucleus, snRNPs are concentrated in coiled bodies and in the speckled regions, whereas SC-35 is found in speckles but not in coiled bodies.
Specificity
Immunogen
Application
- fluorescence image analysis
- immunohistochemistry
- two or three color immunofluorescence staining
- enzyme-linked immunosorbent assay (ELISA)
- immunohistology
- immunoelectronmicroscopy
- immunoaffinity purification
- immunoprecipitation
Indirect immunofluorescence: a dilution of at least 1:2,000 was determined by staining cultured human fibroblasts.
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Storage Class
10 - Combustible liquids
wgk_germany
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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