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S4701

Sigma-Aldrich

Suplatast tosylate

≥98% (HPLC)

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Synonym(s):
(+/-)-[2-[4-(3-ethoxy-2-hydroxypropoxy)phenylcarbamoyl]-ethyl] dimethylsulfonium p-toluenesulfonate, IPD-1151T, ST
Empirical Formula (Hill Notation):
C16H26SNO4 · C7H7SO3
CAS Number:
Molecular Weight:
499.64
MDL number:
PubChem Substance ID:
NACRES:
NA.77

Quality Level

assay

≥98% (HPLC)

form

powder

color

white to off-white

solubility

DMSO: >20 mg/mL

storage temp.

room temp

SMILES string

Cc1ccc(cc1)S([O-])(=O)=O.CCOCC(O)COc2ccc(NC(=O)CC[S+](C)C)cc2

InChI

1S/C16H25NO4S.C7H8O3S/c1-4-20-11-14(18)12-21-15-7-5-13(6-8-15)17-16(19)9-10-22(2)3;1-6-2-4-7(5-3-6)11(8,9)10/h5-8,14,18H,4,9-12H2,1-3H3;2-5H,1H3,(H,8,9,10)

InChI key

RYVJQEZJUFRANT-UHFFFAOYSA-N

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vibrant-m

S4701

Suplatast tosylate

vibrant-m

SML1495

Suprofen

vibrant-m

SML1369

Tesaglitazar

vibrant-m

SML0284

Mycophenolate mofetil

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

room temp

storage temp.

room temp

storage temp.

room temp

storage temp.

room temp

solubility

DMSO: >20 mg/mL

solubility

DMSO: 20 mg/mL, clear

solubility

DMSO: 20 mg/mL, clear

solubility

DMSO: ≥15 mg/mL

color

white to off-white

color

white to beige

color

white to beige

color

white to beige

Application

Suplatast tosylate may be used in immune-signaling studies.

Biochem/physiol Actions

Suplatast tosylate is a dimethylsulfonium compound downregulates the expression of histamine H1 receptor gene, suppresses the activity of histidine decarboxylase and regulates IL-4 mRNA. It inhibits the release of histamines and regulates the production of IgE.1,2 Suplatast tosylate is effective in the treatment of mild-to-moderate persistent asthma in children.3
Suplatast tosylate is an anti-allergy, cytokine modulator.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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