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SAB2500895

Sigma-Aldrich

Anti-RPE65 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

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Synonym(s):
Anti-LCA2, Anti-RP20, Anti-Rd12, Anti-Retinal pigment epithelium-specific protein 65 kDa, Anti-SRPE65
NACRES:
NA.41

biological source

goat

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human, canine

technique(s)

indirect ELISA: suitable
western blot: suitable

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... RPE65(6121)

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This Item
MABN2438SAB2500828SAB2501272
Anti-RPE65 Antibody, clone KPSA1

MABN2438

Anti-RPE65 Antibody, clone KPSA1

conjugate

unconjugated

conjugate

-

conjugate

unconjugated

conjugate

unconjugated

biological source

goat

biological source

mouse

biological source

goat

biological source

goat

shipped in

dry ice

shipped in

-

shipped in

dry ice

shipped in

dry ice

Gene Information

human ... RPE65(6121)

Gene Information

human ... RPE65(6121)

Gene Information

human ... PRPF31(26121)

Gene Information

human ... PDPN(10630)

storage temp.

−20°C

storage temp.

-

storage temp.

−20°C

storage temp.

−20°C

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Immunogen

Peptide with sequence C-EVKKNARKAPQPE from the internal region of the protein sequence according to NP_000320.1.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


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Hamid Aboutaleb Kadkhodaeian et al.
Tissue engineering and regenerative medicine, 16(3), 253-263 (2019-06-18)
Retinal degeneration causes blindness, and cell replacement is a potential therapy. The purpose of this study is to formation of pigmented neurospheres in a simple medium, low-cost, high-performance manner over a short period of time while expressing markers of RPE
Xiaokun Wang et al.
Journal of tissue engineering and regenerative medicine, 12(3), 821-829 (2017-10-20)
Structural and biochemical cues of extracellular matrix can substantially influence the differentiation and maturation of cultured retinal pigment epithelial (RPE) cells. In this study, thin collagen vitrigels were engineered to create collagen nanofibrillar structures of different fibril densities in an
Jianing Gu et al.
Acta biomaterialia, 92, 115-131 (2019-05-11)
In vitro generation of a functional retinal pigment epithelium (RPE) monolayer sheet is useful and promising for RPE cell therapy. Here, for the first time, we used induced pluripotent stem (iPS) supernatant as the conditioned medium (iPS-CM) and femtosecond laser
Yan Li et al.
Human mutation, 40(4), 426-443 (2019-01-11)
Human RPE65 mutations cause a spectrum of retinal dystrophies that result in blindness. While RPE65 mutations have been almost invariably recessively inherited, a c.1430A>G (p.(D477G)) mutation has been reported to cause autosomal dominant retinitis pigmentosa (adRP). To study the pathogenesis
Yi Liao et al.
Investigative ophthalmology & visual science, 60(8), 3034-3045 (2019-07-17)
Visual (retinoid) cycle anomalies induce aberrant build-up of all-trans retinal (atRAL) in the retinal pigment epithelium (RPE), which is a cause of RPE atrophy in Stargardt disease type 1 and age-related macular degeneration. NLR family pyrin domain containing 3 (NLRP3)

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