SAB3501220

Anti-Avian Influenza H5N1 Hemagglutinin (IN1) antibody produced in goat

affinity isolated antibody

• UNSPSC Code: 12352203
• NACRES: NA.43

Properties

• biological source: goat
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: liquid
• species reactivity: influenza A virus (avian | subtype H5N1)
• concentration: 1 mg/mL
• technique(s): ELISA: suitable; western blot: suitable
• isotype: IgG
• UniProt accession no.: Q692M2
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified

Description

General description

Avian Influenza Hemagglutinin 3 Antibody: Influenza A virus is a major public health threat, killing more than 30, 000 people per year in the USA. Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals; however it is in birds that all subtypes can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. During 1997, an H5N1 avian influenza virus was determined to be the cause of death in 6 of 18 infected patients in Hong Kong. There was some evidence of human to human spread of this virus, but it is thought that the transmission efficiency was fairly low. HA interacts with cell surface proteins containing oligosaccharides with terminal sialyl residues. Virus isolated from a human infected with the H5N1 strain in 1997 could bind to oligosaccharides from human as well as avian sources, indicating its species-jumping ability.

Immunogen

Avian Influenza H5N1 Hemagglutinin (IN1) Antibody was raised against a synthetic peptide corresponding to 14 amino acids near the center of the Hemagglutinin protein Efforts were made to use relatively conserved regions of the viral sequence as the antigen.The immunogen is located within amino acids 250 - 300 of Avian Influenza H5N1 Hemagglutinin (IN1) Antibody.

Application

Avian Influenza Hemagglutinin 3 antibody can be used for the detection of the Hemagglutinin protein from the H5N1 strain of avian influenza A in ELISA. It will detect 10 ng of free peptide at 1 μg/mL.

Physical form

Supplied in PBS containing 0.02% sodium azide.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable