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SAB4300426

Sigma-Aldrich

Anti-NOS1 (Ab-852) antibody produced in rabbit

affinity isolated antibody

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Synonym(s):
Anti-IHPS1 antibody produced in rabbit, Anti-NOS antibody produced in rabbit, Anti-nNOS antibody produced in rabbit, Anti-nitric oxide synthase 1 (neuronal) antibody produced in rabbit
MDL number:
NACRES:
NA.41

biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

~160 kDa

species reactivity

mouse, rat, human

concentration

1 mg/mL

technique(s)

indirect immunofluorescence: 1:100-1:200

isotype

IgG

immunogen sequence

(F-N-S-V-S)

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... NOS1(4842)

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SAB4300410SAB4300397SAB4300464
biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

rabbit

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

form

buffered aqueous solution

form

buffered aqueous solution

form

buffered aqueous solution

form

buffered aqueous solution

Gene Information

human ... NOS1(4842)

Gene Information

human ... FOXO1(2308)

Gene Information

human ... MYOD1(4654)

Gene Information

human ... APP(351)

mol wt

~160 kDa

mol wt

78-82 kDa

mol wt

~40 kDa

mol wt

100-140 kDa

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General description

NOS1 (nitric oxide synthase 1) is one of the NOS (nitric oxide synthase) isoforms found in the heart. It is located on human chromosome 12q24.2-31. It is mainly localized in the sarcoplasmic reticulum (SR).

Immunogen

Peptide sequence around aa. 850-854 (F-N-S-V-S), according to the protein NOS1.

Application

Anti-NOS1 (Ab-852) antibody has been used in immunocytochemistry .

Biochem/physiol Actions

NOS (nitric oxide synthase) produce nitric oxide in the heart.It regulates myocardial function and plays an important role in the remodeling of human (ICM) ischemic cardiomyopathy.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Target description

Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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Converging evidence for an impact of a functional NOS gene variation on anxiety-related processes
Kuhn M, et al.
Social Cognitive and Affective Neuroscience, 11(5), 803-812 (2016)
Ana C Bahia et al.
PLoS neglected tropical diseases, 5(11), e1317-e1317 (2011-11-10)
Malaria affects 300 million people worldwide every year and 450,000 in Brazil. In coastal areas of Brazil, the main malaria vector is Anopheles aquasalis, and Plasmodium vivax is responsible for the majority of malaria cases in the Americas. Insects possess
The JAK-STAT pathway controls Plasmodium vivax load in early stages of Anopheles aquasalis infection
Bahia AC, et al.
PLoS Neglected Tropical Diseases, 5(11) (2011)
Roles of nitric oxide and superoxide in inflammation.
Daniela Salvemini et al.
Methods in molecular biology (Clifton, N.J.), 225, 291-303 (2003-05-29)

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