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SAB5700363

Sigma-Aldrich

Anti-Phospho-NF-kB p65-S536 antibody produced in rabbit

Synonym(s):

CMCU, NF-kB p65, NFKB3, RELA, p65

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

58
59
60

species reactivity

rat, mouse, human

concentration

1.11 mg/ml

technique(s)

immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pSer536)

Gene Information

human ... RELA(5970)

General description

NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.

Immunogen

A phospho specific peptide corresponding to residues surrounding S536 of human NF-kB p65

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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