SAB5700572

Anti-Phospho-ATP1A1-S16 antibody produced in rabbit

• Synonym(s): ATP1A, ATP1A1, ATPase Na+/K+ transporting subunit alpha 1, CMT2DD, HOMGSMR2
• UNSPSC Code: 12352203
• NACRES: NA.43

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: 112
• species reactivity: human, mouse, rat
• concentration: 0.73mg/ml
• technique(s): western blot: 1:500-1:2000
• UniProt accession no.: P05023
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pSer16)
• Gene Information: human ... ATP1A1(476)

Description

General description

The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene.

Immunogen

A phospho specific peptide corresponding to residues surrounding S16 of human ATP1A1.

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable