SML1122

BTB06584

≥98% (HPLC)

• Synonym(s): 2-Nitro-5-(phenylsulfonyl)phenyl 4-chloro-benzoic acid
• Empirical Formula (Hill Notation): C₁₉H₁₂ClNO₆S
• CAS Number: 219793-45-0
• Molecular Weight: 417.82
• MDL number: MFCD00103060
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825662
• NACRES: NA.77

Properties

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 20 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: O=S(C1=CC=C([N+]([O-])=O)C(OC(C2=CC=C(Cl)C=C2)=O)=C1)(C3=CC=CC=C3)=O
• InChI: 1S/C19H12ClNO6S/c20-14-8-6-13(7-9-14)19(22)27-18-12-16(10-11-17(18)21(23)24)28(25,26)15-4-2-1-3-5-15/h1-12H
• InChI key: WNDWKKPBLAKXMI-UHFFFAOYSA-N

Description

Biochem/physiol Actions

BTB06584 inhibits the ATP hydrolase activity of mitochondrial F1F0 ATP synthase. The compound BTB06584 has no affect on oxygen consumption or mitochondrial membrane potential in HL-1, a mouse cardiac cell line, but blocks ATP consumption and ischemic cell death following inhibition of cellular respiration.

Safety Information

• pictograms: GHS05
• signalword: Danger
• hcodes: H318
• pcodes: P280 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable