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SML3037

Sigma-Aldrich

MTSSL

≥98% (HPLC)

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Synonym(s):
(1-Oxyl-2,2,5,5-tetramethyl-3-pyrroline-3-methyl)methanethiosulfonate, 1H-Pyrrol-1-yloxy, 2,5-dihydro-2,2,5,5-tetramethyl-3-[[(methylsulfonyl)thio]methyl]-, 2,5-Dihydro-2,2,5,5-tetramethyl-3-[[(methylsulfonyl)thio]methyl]-1H-pyrrol-1-yloxy, MTS, MTS (spin label), MTSL
Empirical Formula (Hill Notation):
C10H18NO3S2
CAS Number:
Molecular Weight:
264.38
MDL number:

Quality Level

assay

≥98% (HPLC)

form

powder

storage condition

protect from light

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

−20°C

SMILES string

[O]N1C(C)(C)C=C(C1(C)C)CSS(=O)(C)=O

InChI

1S/C10H18NO3S2/c1-9(2)6-8(7-15-16(5,13)14)10(3,4)11(9)12/h6H,7H2,1-5H3

InChI key

BLSCGBLQCTWVPO-UHFFFAOYSA-N

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F131PZ0367SML0203
MTSSL ≥98% (HPLC)

SML3037

MTSSL

FPL 64176 ≥98% (HPLC), powder

F131

FPL 64176

PF-02413873 ≥98% (HPLC)

PZ0367

PF-02413873

iCRT14 ≥98% (HPLC)

SML0203

iCRT14

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

-

Quality Level

100

Quality Level

100

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

room temp

storage temp.

2-8°C

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: >20 mg/mL (Solutions should be freshly prepared.), H2O: insoluble

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: ≥10 mg/mL

storage condition

protect from light

storage condition

desiccated, protect from light

storage condition

-

storage condition

-

Biochem/physiol Actions

MTSSL is a cysteine-specific, flexible disulfide bond forming paramagnetic nitroxide spin label probe. MTSSL is reported to be useful for investigating structural and conformational dynamics of membrane proteins and protein aggregation.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Marilena Di Valentin et al.
Biochimica et biophysica acta, 1857(12), 1909-1916 (2016-10-26)
Triplet-triplet energy transfer from chlorophylls to carotenoids is the mechanism underlying the photoprotective role played by carotenoids in many light harvesting complexes, during photosynthesis. The peridinin-chlorophyll-a protein (PCP) is a water-soluble light harvesting protein of the dinoflagellate Amphidinium carterae, employing
Thomas H Edwards et al.
Journal of magnetic resonance (San Diego, Calif. : 1997), 288, 58-68 (2018-02-08)
Tikhonov regularization is the most commonly used method for extracting distance distributions from experimental double electron-electron resonance (DEER) spectroscopy data. This method requires the selection of a regularization parameter, α, and a regularization operator, L. We analyze the performance of
Alise R Muok et al.
Applied magnetic resonance, 49(12), 1385-1395 (2019-01-29)
Site-directed spin labeling of proteins by chemical modification of engineered cysteine residues with the molecule MTSSL (1-Oxyl-2,2,5,5-tetramethylpyrroline-3-methyl methanethiosulfonate) has been an invaluable tool for conducting double electron electron resonance (DEER) spectroscopy experiments. However, this method is generally limited to recombinant

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