SML3366
SIS17
≥95% (HPLC)
Synonym(s):
N′-Hexadecylthiophene-2-carbohydrazide, SIS 17, SIS-17
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About This Item
Empirical Formula (Hill Notation):
C21H38N2OS
CAS Number:
Molecular Weight:
366.60
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.77
Recommended Products
Quality Level
assay
≥95% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear (Warmed)
storage temp.
-10 to -25°C
Biochem/physiol Actions
SIS17 is a potent and selective HDAC11 inhibitor (IC50 = 830 nM; IC50 >100 μM against HDAC1/4/8 or SIRT1/2/3/6) that effectively upregulates HDAC11 substrate, serine hydroxymethyl transferase 2 (SHMT2), fatty acylation level in MCF7 cells (12.5 μM).
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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