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SML4075

Sigma-Aldrich

Ginsenoside Rg1

new

≥98% (HPLC)

Synonym(s):

(3β,6α,12β)-3,12-Dihydroxydammar-24-ene-6,20-diyl bis-β-D-glucopyranoside, Ginsenoside A2, Ginsenoside g1, Panaxoside A, Panaxoside Rg1, Panaxsaponin Rg1, Rg1 ginsenoside, Sanchinoside C1, Sanchinoside Rg1

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About This Item

Empirical Formula (Hill Notation):
C42H72O14
CAS Number:
Molecular Weight:
801.01
MDL number:
UNSPSC Code:
12352200

biological source

Panax notoginseng (Burk.) F.H.Chen

Quality Level

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: soluble mg/mL, clear

storage temp.

-10 to -25°C

Biochem/physiol Actions

Major component of Panax ginseng that exhibits a variety of pharmacological actions including regulation of organ function regulation of adult stem cells, inhibition of autophagy and endoplasmic reticulum stress, antioxidant, anti-inflammatory, and metabolic modulation.
Ginsenoside Rg1, a key component of Panax ginseng, is a tetracyclic triterpenoid derivative that displays various pharmacological properties such as regulating organ function, regulating adult stem cells, inhibiting autophagy and endoplasmic reticulum stress to protect cardiac function, antioxidant, anti-inflammatory, and metabolic modulation. Ginsenoside Rg1 has also been found to be an effective regulator of mesenchymal stem cells and to have a positive effect on hepatic steatosis.

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Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Huimin Zhou et al.
Journal of ethnopharmacology, 324, 117794-117794 (2024-01-21)
Ginseng (Panax ginseng C. A. Meyer) is a precious traditional Chinese medicine with multiple pharmacological effects. Ginsenoside Rg1 is a main active ingredient extracted from ginseng, which is known for its age-delaying and antioxidant effects. Increasing evidence indicates that Rg1
Jun Guo et al.
Journal of leukocyte biology, 112(5), 1065-1077 (2022-07-02)
Acute kidney injury (AKI) represents a prevailing complication of sepsis, and its onset involves ferroptosis. Ginsenoside Rg1 exerts a positive effect on kidney diseases. This study explored the action of ginsenoside Rg1 in sepsis-induced AKI (SI-AKI) by regulating ferroptosis in
Qian Xie et al.
Frontiers in pharmacology, 14, 1179705-1179705 (2023-09-25)
Background: According to existing laboratory data, ginsenoside Rg1 may help cure diabetes and its complications by reducing oxidative stress (OS) and managing inflammation. However, this conclusion lacks reliability and is unclear. As a result, the purpose of this systematic review

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