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SRE0081

Sigma-Aldrich

CaseiNSBlock

Suitable for manufacturing of diagnostic kits and reagents, Casein, alkali treated

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Synonym(s):
Casein from bovine milk
CAS Number:
MDL number:
NACRES:
NA.61

biological source

bovine

Quality Level

form

powder

concentration

≥90 % protein (dry)

technique(s)

enzyme immunoassay: suitable

mp

280 °C (dec.) (lit.)

UniProt accession no.

storage temp.

2-8°C

InChI

1S/C81H125N22O39P/c1-36(2)31-50(76(132)94-43(15-24-57(87)108)71(127)101-52(34-64(120)121)78(134)98-49(81(137)138)11-7-8-30-82)99-72(128)47(19-28-61(114)115)95-77(133)51(33-63(118)119)100-73(129)48(20-29-62(116)117)97-80(136)65(37(3)104)103-75(131)44(16-25-58(88)109)92-68(124)42(14-23-56(86)107)90-67(123)41(13-22-55(85)106)91-69(125)45(17-26-59(110)111)93-70(126)46(18-27-60(112)113)96-79(135)53(35-142-143(139,140)141)102-74(130)40(12-21-54(84)105)89-66(122)39(83)32-38-9-5-4-6-10-38/h4-6,9-10,36-37,39-53,65,104H,7-8,11-35,82-83H2,1-3H3,(H2,84,105)(H2,85,106)(H2,86,107)(H2,87,108)(H2,88,109)(H,89,122)(H,90,123)(H,91,125)(H,92,124)(H,93,126)(H,94,132)(H,95,133)(H,96,135)(H,97,136)(H,98,134)(H,99,128)(H,100,129)(H,101,127)(H,102,130)(H,103,131)(H,110,111)(H,112,113)(H,114,115)(H,116,117)(H,118,119)(H,120,121)(H,137,138)(H2,139,140,141)

InChI key

BECPQYXYKAMYBN-UHFFFAOYSA-N

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This Item
E0789C9801C5890
CaseiNSBlock Suitable for manufacturing of diagnostic kits and reagents, Casein, alkali treated

Sigma-Aldrich

SRE0081

CaseiNSBlock

form

powder

form

powder

form

essentially salt-free, lyophilized powder

form

purified powder

concentration

≥90 % protein (dry)

concentration

-

concentration

-

concentration

-

technique(s)

enzyme immunoassay: suitable

technique(s)

enzyme immunoassay: suitable

technique(s)

activity assay: suitable

technique(s)

activity assay: suitable, electrophoresis: suitable, immunocytochemistry: suitable

UniProt accession no.

P02662, P02663, P02666, P02668

UniProt accession no.

P02662, P02663, P02666, P02668

UniProt accession no.

P02662, P02663, P02666, P02668

UniProt accession no.

P02662, P02663, P02666, P02668

storage temp.

2-8°C

storage temp.

room temp

storage temp.

−20°C

storage temp.

-

Application

CaseiNSBlock alkaline treated casein is developed for use in immunoassay to remove non-specific binding and to reduce background. It is suitable for manufacturing of immunoassay buffers due to improved solubility in biological matrices compared to other forms of casein. Provides excellent blocking on all membranes and plates.

Biochem/physiol Actions

Partial gastrointestinal digestion of casein is a rich source of bioactive peptides, such as β-casomorphin. However, bovine casein is not homogeneous; variants A1 and B do lead to production of β-casomorphin 7 production, while A2 does not.

Preparation Note

Alkaline treated casein formulated to remove nonspecific binding in immunoassays

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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