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SRP8032

Sigma-Aldrich

IL-1 Receptor Type I (human): FC (human)

recombinant, expressed in HEK 293 cells, >95% (SDS-PAGE)

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Synonym(s):
Interleukin-1 receptor alpha, Interleukin-1 receptor type I, RI, Serpin F1
NACRES:
NA.32

biological source

human

recombinant

expressed in HEK 293 cells

assay

>95% (SDS-PAGE)

form

lyophilized

mol wt

~80 kDa by SDS-PAGE

packaging

pkg of 50 μg

storage condition

avoid repeated freeze/thaw cycles

impurities

<0.1 EU/μg endotoxin, tested

color

white

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... IL1R1(3554)

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This Item
SRP3327SRP8033SRP8053
Sigma-Aldrich

SRP3327

IL-1 RECEPTOR ANTAGONIST human

Sigma-Aldrich

SRP8033

IL-1β mouse

Sigma-Aldrich

SRP8053

IL-35 (mouse): FC (human)

recombinant

expressed in HEK 293 cells

recombinant

expressed in E. coli

recombinant

expressed in E. coli

recombinant

expressed in CHO cells

biological source

human

biological source

human

biological source

mouse

biological source

human, mouse

mol wt

~80 kDa by SDS-PAGE

mol wt

17.2 kDa

mol wt

~17 kDa by SDS-PAGE

mol wt

monomer 23 kDa by calculation (IL-12a (p35)), monomer 46 kDa by calculation (Ebi3)

form

lyophilized

form

lyophilized

form

lyophilized

form

lyophilized

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

General description

IL-1RI is the receptor for interleukin-1 alpha (IL-1A), beta (IL-1B), and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappaB. Signaling involves formation of a ternary complex containing IL1RAP, leading the activation of TOLLIP, MYD88, and IRAK1 or IRAK2.

Physical form

Lyophilized from PBS.

Reconstitution

Reconstitute with 50 μL deionized water.

Other Notes

Human IL-1RI (interleukin-1 receptor type I) (aa 21-336) is fused at the C-terminus to the Fc portion of human IgG1.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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