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T0647

Sigma-Aldrich

TAPS sodium salt

≥99% (titration)

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Synonym(s):
3-[N,N-Bis(2-hydroxyethyl)amino]-2-hydroxypropanesulfonic acid sodium salt, TAPS NA, N-tris(Hydroxymethyl)methyl-3-aminopropanesulfonic acid sodium-potassium salt, [(2-Hydroxy-1,1-bis(hydroxymethyl)ethyl)amino]-1-propanesulfonic acid sodium-potassium salt
Empirical Formula (Hill Notation):
C7H16NNaO6S
CAS Number:
Molecular Weight:
265.26
MDL number:
PubChem Substance ID:
NACRES:
NA.25

Quality Level

assay

≥99% (titration)

form

crystalline powder

impurities

≤1% water content (Karl Fischer)

useful pH range

7.7-9.1

pKa (25 °C)

8.4

solubility

water: 0.33 g/mL, clear to slightly hazy, colorless

cation traces

Pb: ≤5 ppm

application(s)

diagnostic assay manufacturing

SMILES string

[Na+].OCC(CO)(CO)NCCCS([O-])(=O)=O

InChI

1S/C7H17NO6S.Na/c9-4-7(5-10,6-11)8-2-1-3-15(12,13)14;/h8-11H,1-6H2,(H,12,13,14);/q;+1/p-1

InChI key

FEGYIWVHCSRXCG-UHFFFAOYSA-M

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This Item
T5441T5130T0772
TAPS sodium salt ≥99% (titration)

T0647

TAPS sodium salt

-
TAPS sodium salt BioPerformance Certified, suitable for cell culture, ≥99%

T5441

TAPS sodium salt

Premium Grade
TAPS ≥99.5% (titration)

T5130

TAPS

-
TES sodium salt ≥99% (titration)

T0772

TES sodium salt

-
Quality Level

200

Quality Level

200

Quality Level

400

Quality Level

200

form

crystalline powder

form

crystalline powder

form

crystalline powder

form

crystalline powder

application(s)

diagnostic assay manufacturing

application(s)

diagnostic assay manufacturing

application(s)

diagnostic assay manufacturing

application(s)

diagnostic assay manufacturing

solubility

water: 0.33 g/mL, clear to slightly hazy, colorless

solubility

water: 0.33 g/mL, clear to slightly hazy, colorless

solubility

water: 0.5 g/mL, clear, colorless

solubility

water: 0.333 g/mL, clear to slightly hazy, colorless

cation traces

Pb: ≤5 ppm

cation traces

heavy metals (as Pb): ≤5 ppm

cation traces

-

cation traces

Pb: ≤5 ppm

General description

N-Tris(hydroxymethyl)methyl-3-aminopropanesulfonic acid (TAPS) is a zwitterionic ionic buffer that is widely used in capillary electrophoresis. As one of the key biological buffers, it maintains the required pH of the medium and exhibits various properties such as high water soluble, highly inert, and stable nature and extremely low absorbance of ultraviolet-visible (UV-vis) light. TAPS buffer also aids in stabilizing lysozyme against thermal denaturation. It is widely used in biology and biochemistry.

Application

TAPS sodium salt has been used along with filtered natural sea water (FSW) to stain live or fixed embryos.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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The effects of biological buffers TRIS, TAPS, TES on the stability of lysozyme
Pannuru P, et al.
International Journal of Biological Macromolecules, 112, 720-727 (2018)
Buffer Standards for the Physiological pH of the Zwitterionic Compound, TAPS, From 5 to 55? C
Roy L N, et al.
Journal of Solution Chemistry, 35, 551-566 (2006)
Capillary electrophoretic study of interactions of metal ions with crown ethers, a sulfated beta-cyclodextrin, and zwitterionic buffers present as additives in the background electrolyte
Muzikar M, et al.
Electrophoresis, 23(12) , 1796-802 (2002)

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