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Monoclonal Anti-Troponin T antibody produced in mouse

clone JLT-12, ascites fluid

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Anti-ANM, Anti-NEM5, Anti-STNT, Anti-TNT, Anti-TNTS
MDL number:

biological source


Quality Level



antibody form

ascites fluid

antibody product type

primary antibodies


JLT-12, monoclonal


15 mM sodium azide

species reactivity

chicken, rat, bovine, rabbit


immunohistochemistry: suitable
western blot: 1:200 using rabbit total skeletal muscle extract



UniProt accession no.

shipped in

dry ice

storage temp.


target post-translational modification


Gene Information

Related Categories

General description

Monoclonal Anti-Troponin T (mouse IgG1 isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse.
Troponin T is a vital subunit of troponin. Troponin T is a comma or rod shaped protein with a length of 185-205 Å. Troponin T is positioned in the actin helix groove and is extended along the filament of troponin. Life span of serum troponin T is 120 minutes. N- terminal end of the protein is enriched in negatively charged residues and C- terminal end is enriched with positively charged residues. This uneven distribution of charges in troponin T facilitates its aggregation at physiological salt concentration. In humans, cardiac troponin T exists in four isoforms, out of which three are expressed in the fetus and one isoform is expressed in the adult heart.


Troponin T from rabbit skeletal muscle.


Monoclonal Anti-Troponin T antibody produced in mouse has been used in following studies:
  • Western blot analysis.
  • Immunocytochemical analysis.
  • Immunofluorescence.
Monoclonal Anti-Troponin T antibody produced in mouse has been used in immunostaining.

Biochem/physiol Actions

Troponin T is a subunit of troponin, which facilitates binding of troponin to tropomyosin. It also plays a crucial role in muscle contraction. Cardiac troponin T acts as a potential marker for the detection of acute myocardial infarction (MI). Apart from facilitating binding of troponin components to the actin-tropomyosin filament, it is has an essential role in the regulation of actomyosin ATPase activity. Cardiac troponin T gene mutation leads to hypertrophic cardiomyopathy.


Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class

10 - Combustible liquids




Not applicable


Not applicable

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