All Photos(1)



Nalgene® bottle-top sterile filter units

filter capacity 500 mL, pore size 0.2 μm, fits 45 mm bottle neck

Sign Into View Organizational & Contract Pricing

bottletop filtration, rapid-flow filter, sterile culture media filter, vacuum filtration


polyethersulfone membrane
polystyrene housing






pack of 12 ea


Nalgene® 595-4520


75 mm

filter capacity

500 mL

funnel capacity

500 mL

neck diam.

45 mm

pore size

0.2 μm

Looking for similar products? Visit Product Comparison Guide


Nalgene® bottle-top sterile filter units are suitable for the filtration of cell culture media, additives, serum, and buffers.

Features and Benefits

Nalgene® bottle-top sterile filter units have the following benefits:
  • Polyethersulfone (PES) membrane is best suited for tissue culture.
  • Faster results and less waiting time.
  • Non-pyrogenic and endotoxin free.
  • PES exhibits low protein binding, resulting in low chances of loss of protein from media.
  • PES is hydrophilic and thus does not require external wetting agents or surfactants.
  • PES offers higher aqueous flow rates.
  • PES has greater strength, capacity, and chemical resistance than cellulose acetate, nitrocellulose, or nylon.
  • Polystyrene body with graduations.

Legal Information

Nalgene is a registered trademark of Thermo Fisher Scientific or its subsidiaries

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).


Product Number
Pack Size/Quantity

Additional examples:





enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service