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47858

Supelco

Thiamine Hydrochloride (B1)

analytical standard

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Synonym(s):
Thiamine hydrochloride, Aneurine hydrochloride, Vitamin B1 hydrochloride
Empirical Formula (Hill Notation):
C12H17ClN4OS · HCl
CAS Number:
Molecular Weight:
337.27
Beilstein:
3851771
EC Number:
MDL number:
PubChem Substance ID:

grade

analytical standard

Quality Level

CofA

current certificate can be downloaded

feature

standard type water soluble vitamin

packaging

ampule of 1000 mg

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

250 °C (dec.) (lit.)

application(s)

pharmaceutical (small molecule)
vitamins, nutraceuticals, and natural products

format

neat

storage temp.

2-30°C

SMILES string

CC1=NC(N)=C(C[N+]2=CSC(CCO)=C2C)C=N1.Cl.[Cl-]

InChI

1S/C12H17N4OS.2ClH/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13;;/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15);2*1H/q+1;;/p-1

InChI key

DPJRMOMPQZCRJU-UHFFFAOYSA-M

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This Item
T4562T4625PHR1037
Thiamine Hydrochloride (B1) analytical standard

Supelco

47858

Thiamine Hydrochloride (B1)

-
Thiamine hydrochloride meets USP testing specifications

Sigma-Aldrich

T4562

Thiamine hydrochloride

-
Thiamine hydrochloride reagent grade, ≥99% (HPLC)

Sigma-Aldrich

T4625

Thiamine hydrochloride

Essential Grade
Thiamine hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1037

Thiamine hydrochloride

-
format

neat

format

-

format

-

format

neat

CofA

current certificate can be downloaded

CofA

-

CofA

-

CofA

current certificate can be downloaded

feature

standard type water soluble vitamin

feature

-

feature

-

feature

-

packaging

ampule of 1000 mg

packaging

-

packaging

-

packaging

-

technique(s)

HPLC: suitable

technique(s)

-

technique(s)

HPLC: suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

General description

Thiamine hydrochloride (B1) is a water soluble vitamin, which belongs the B-complex group of vitamins. It can exist both as a hemihydrate and as a nonstoichiometric hydrate. It can generally act like a co-enzyme for biochemical reactions involved in carbohydrate metabolism.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Thiamine Hydrochloride (B1) may be used as an analytical reference standard for the quantification of the analyte in pharmaceutical formulations using high-performance liquid chromatography (HPLC) technique.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

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In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

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Thiamine hydrochloride European Pharmacopoeia (EP) Reference Standard

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Thiamine hydrochloride

Cyanocobalamin (B12) analytical standard

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47869

Cyanocobalamin (B12)

Thiamine hydrochloride meets USP testing specifications

Sigma-Aldrich

T4562

Thiamine hydrochloride

L-Ascorbic acid analytical standard

Supelco

47863

L-Ascorbic acid

Thiamine hydrochloride tested according to Ph. Eur.

Sigma-Aldrich

04573

Thiamine hydrochloride

Wanamaker.PB and Massey K
Applied Pharmacology for Veterinary Technicians, (5) (2014)
Insights into the dehydration behavior of thiamine hydrochloride (Vitamin B1) hydrates: Part II
Chakravarty P, et al.
Journal of Pharmaceutical Sciences, 99(4), 1882-1895 (2010)
Helen Wang et al.
Bio-protocol, 8(16), e2974-e2974 (2018-08-20)
Diatoms are an ecologically important group of eukaryotic microalgae with properties that make them attractive for biotechnological applications such as biofuels, foods, cosmetics and pharmaceuticals. Phaeodactylum tricornutum is a model diatom with defined culture conditions, but routine genetic manipulations are
High-performance liquid chromatography method for the simultaneous determination of thiamine hydrochloride, pyridoxine hydrochloride and cyanocobalamin in pharmaceutical formulations using coulometric electrochemical and ultraviolet detection
Marszall LM, et al.
Journal of Chromatography A, 1094(1-2), 91-98 (2005)
Josefin Engelhardt et al.
PloS one, 15(1), e0227201-e0227201 (2020-01-03)
The eastern Baltic cod (Gadus morhua) population has been decreasing in the Baltic Sea for at least 30 years. Condition indices of the Baltic cod have decreased, and previous studies have suggested that this might be due to overfishing, predation

Protocols

LC/MS/MS Analysis of Vitamins B1 and B6 on Ascentis® Express OH5

Separation of Pyridoxine Hydrochloride (B6), analytical standard; Thiamine Hydrochloride (B1), analytical standard

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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