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58978

Supelco

SUPELCOSIL LC-18-DB HPLC Column

3 μm particle size, L × I.D. 3.3 cm × 4.6 mm

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eCl@ss:
32110501

agency

suitable for USP L1

Quality Level

feature

endcapped

manufacturer/tradename

SUPELCOSIL

extent of labeling

11.0% Carbon loading

parameter

0-70 °C temperature
400 bar pressure (5801 psi)

technique(s)

HPLC: suitable

L × I.D.

3.3 cm × 4.6 mm

surface area

170 m2/g

surface coverage

surface coverage 3.1 μmol/m2

matrix

silica gel, spherical particle platform

matrix active group

C18 (octadecyl) phase

particle size

3 μm

pore size

120 Å

application(s)

food and beverages

separation technique

reversed phase

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This Item
589925899359164
Supelco

58978

SUPELCOSIL LC-18-DB HPLC Column

Supelco

58992

SUPELCOSIL LC-18-DB HPLC Column

SUPELCOSIL™ LC-18-DB HPLC Column 3 μm particle size, L × I.D. 15 cm × 4.6 mm

58993

SUPELCOSIL LC-18-DB HPLC Column

Supelco

59164

SUPELCOSIL LC-18-DB HPLC Column

matrix

silica gel, spherical particle platform

matrix

silica gel, spherical particle platform

matrix

silica gel, spherical particle platform

matrix

silica gel, spherical particle platform

separation technique

reversed phase

separation technique

reversed phase

separation technique

reversed phase

separation technique

reversed phase

particle size

3 μm

particle size

3 μm

particle size

3 μm

particle size

5 μm

pore size

120 Å

pore size

120 Å

pore size

120 Å

pore size

120 Å

agency

suitable for USP L1

agency

suitable for USP L1

agency

suitable for USP L1

agency

suitable for USP L1

General description

SUPELCOSIL LC-DB phases are specially deactivated for basic compounds. These columns provide shorter retention, better peak shape, and higher efficiency for organic bases than can be obtained on other Type A silica reversed-phase columns.

Application

SUPELCOSIL LC-18-DB HPLC column may be used in the determination of 8-oxoguanine in samples of deoxyribonucleic acid (DNA) using gas chromatography coupled with mass spectrometry (GC-MS)and reversed-phase high performance liquid chromatography coupled with electrochemical detection (HPLC-EC)

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Legal Information

SUPELCOSIL is a trademark of Sigma-Aldrich Co. LLC

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Determination of 8-oxoguanine in DNA by gas chromatography-mass spectrometry and HPLC-electrochemical detection: overestimation of the background level of the oxidized base by the gas chromatography-mass spectrometry assay.
Ravanat L-J, et al.
Chemical Research in Toxicology, 8(8), 1039-1045 (1995)
J S Patrick et al.
Analytical biochemistry, 199(1), 125-131 (1991-11-15)
A rapid, isocratic method for the determination of tryptophan in Escherichia coli fermentation broths by reversed-phase HPLC is described. Tryptophan can be measured in fermentations containing either chemically defined media or media with hydrolyzed protein supplements. The procedure was rugged
P K Kunicki
Journal of chromatography. B, Biomedical sciences and applications, 755(1-2), 331-335 (2001-06-08)
A HPLC-UV determination of loratadine in human plasma is presented. After simple liquid-liquid extraction with 2-methylbutane-hexane (2:1) and evaporation of organic phase the compounds were re-dissolved in 0.01 M HCl, evaporated again and finally separated on a Supelcosil LC-18-DB column.
E Terjéki et al.
Journal of pharmaceutical and biomedical analysis, 24(5-6), 913-920 (2001-03-15)
RGH-1756 (1-(2-methoxy-phenyl)-4-(4-[4-(6-imidazo[2,1-b]-thiazolyl)-phenoxy]-butyl)-piperazine dimethansulphonate) is a novel atypical antipsychotic candidate of Gedeon Richter Ltd. A new HPLC method has been developed and validated for the quantitative determination of RGH-1756 in dog and rat plasma. The compound and the internal standard are
O Majid et al.
Therapeutic drug monitoring, 23(2), 163-168 (2001-04-11)
Recipients of organ transplants remain particularly dependent on prednisolone as part of their maintenance immunosuppression. Despite this, the pharmacokinetics of prednisolone have never been fully characterized in these patients, and consequently dosing remains empirical. Accurate monitoring of prednisolone, its primary

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