1138405

Clobetasol propionate

United States Pharmacopeia (USP) Reference Standard

• Empirical Formula (Hill Notation): C₂₅H₃₂ClFO₅
• CAS Number: 25122-46-7
• Molecular Weight: 466.97
• MDL number: MFCD00058499
• UNSPSC Code: 41116107
• PubChem Substance ID: 329749426
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• API family: clobetasol
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: CCC(=O)O[C@@]1([C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C(=O)CCl
• InChI: 1S/C25H32ClFO5/c1-5-21(31)32-25(20(30)13-26)14(2)10-18-17-7-6-15-11-16(28)8-9-22(15,3)24(17,27)19(29)12-23(18,25)4/h8-9,11,14,17-19,29H,5-7,10,12-13H2,1-4H3/t14-,17-,18-,19-,22-,23-,24-,25-/m0/s1
• InChI key: CBGUOGMQLZIXBE-XGQKBEPLSA-N
• Gene Information: human ... NR3C1(2908)

Description

General description

Clobetasol propionate is a fluorinated corticosteroid. It is mainly used as topical ointment. It is an anti-inflammatory agent and has been considered as vasoconstrictor in nature.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Clobetasol propionate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Clobetasol Propionate Cream
• Clobetasol Propionate Ointment
• Clobetasol Propionate Topical Solution

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• pictograms: GHS08
• signalword: Danger
• hcodes: H360Df,H373,H413
• pcodes: P202 - P260 - P273 - P280 - P308 + P313 - P405
• Hazard Classifications: Aquatic Chronic 4 - Repr. 1B - STOT RE 2
• target_organs: Adrenal gland,Immune system
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable