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  • Late ureteral obstruction after injection of dextranomer/hyaluronic acid copolymer.

Late ureteral obstruction after injection of dextranomer/hyaluronic acid copolymer.

Urology (2014-01-15)
Samuel Christen, Mario Mendoza, Rita Gobet, Peter Bode, Daniel Weber
ABSTRACT

Various biological and artificial materials have been introduced for endoscopic treatment of vesicoureteral reflux. Over the past years, dextranomer combined with hyaluronic acid (Dx/Ha) has been established as the most commonly used tissue-augmenting substance for subureteral injection because of its biocompatibility. Nevertheless, the histopathologic analysis of failed Dx/Ha injections showed changes in consistency and volume of the deposit and granulomatous reactions of the adjacent tissue. We report a case of late-onset obstruction 2 years after the injection of Dx/Ha. In the current literature, this potential long-term complication is hardly mentioned.

MATERIALS
Product Number
Brand
Product Description

Supelco
Dextran from Leuconostoc mesenteroides, for GPC, analytical standard, Mw 50,000
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Dextran, analytical standard, for GPC, 410,000
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Dextran, analytical standard, for GPC, 80,000
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Dextran from Leuconostoc spp., Mr 450,000-650,000
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Dextran, analytical standard, for GPC, 25,000
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Hyaluronic acid sodium salt from bovine vitreous humor
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