Effect of Morinda citrifolia fruit extract and its iridoid glycosides on blood fluidity.

Effect of Morinda citrifolia fruit extract and its iridoid glycosides on blood fluidity.

Journal of natural medicines (2014-03-08)

Kazuya Murata, Yumi Abe, Megumi Futamura-Masuda, Akemi Uwaya, Fumiyuki Isami, Shixin Deng, Hideaki Matsuda

ABSTRACT

The aim of this study was to investigate the effect of Morinda citrifolia fruit on blood fluidity. M. citrifolia fruit extract (MCF-ext) was investigated for its influence on blood aggregation and fibrinolysis. MCF-ext inhibited polybrene-induced erythrocyte aggregation and thrombin activity. The fibrinolytic activity of MCF-ext, in the euglobulin lysis time test and fibrin plate assay, is reported here for the first time. One of the active compounds was an iridoid glycoside, asperulosidic acid. The results indicated that MCF-ext is a potentially useful health food which is capable of improving blood flow and preventing lifestyle-related diseases.

MATERIALS

Product Number

Brand

Product Description

P0662

Sigma-Aldrich

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04243

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