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TLR9

toll-like receptor 9

Synonyms:
CD289
Species:
UniProtKB ID:
Gene ID:
  • Human(54106) Summary: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response. [provided by RefSeq, Jul 2008]
  • Mouse(81897) toll-like receptor 9
  • Rat(338457) toll-like receptor 9
  • naked mole-rat(101715478) toll-like receptor 9
  • cow(282602) toll-like receptor 9
  • Horse(100009693) toll-like receptor 9
  • sheep(494547) toll-like receptor 9
  • dog(403502) toll-like receptor 9
  • Zebrafish(403128) toll-like receptor 9
  • domestic cat(493839) toll-like receptor 9
  • Goat(100860819) toll-like receptor 9

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Antagonist

Product Number
Description
Species
Hydroxychloroquine sulfate, United States Pharmacopeia (USP) Reference Standard,
Species
human
Hydroxychloroquine sulfate, ≥98% (HPLC), powder,
Species
human
Hydroxychloroquine Sulfate, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
Hydroxychloroquine sulfate, analytical standard,
Species
human
Hydroxychloroquine sulfate, British Pharmacopoeia (BP) Reference Standard,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
ANTI-TLR9 antibody produced in mouse, clone 2H5, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
ANTI-TLR9 antibody produced in mouse, clone 1E4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
ANTI-TLR9 antibody produced in mouse, clone 2G3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
ANTI-TLR9 antibody produced in mouse, clone 2C3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
ANTI-TLR9 antibody produced in mouse, clone 3B7, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human TLR9, RP11-330H6.5,
Species
human
MISSION® esiRNA, targeting human TWF2, RP11-330H6.5,
Species
human