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品質水準
アッセイ
99%
mp
228-230 °C (lit.)
溶解性
water: soluble 1g in 1475ml(lit.)
alcohol: freely soluble(lit.)
diethyl ether: freely soluble(lit.)
hot water: soluble(lit.)
官能基
carboxylic acid
nitro
SMILES記法
OC(=O)c1cc(ccc1O)[N+]([O-])=O
InChI
1S/C7H5NO5/c9-6-2-1-4(8(12)13)3-5(6)7(10)11/h1-3,9H,(H,10,11)
InChI Key
PPDRLQLKHRZIJC-UHFFFAOYSA-N
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詳細
2-Hydroxy-5-nitrobenzoic acid inhibits the activity of wild type-bovine low Mr protein tyrosine phosphatase. The inhibition constant has been evaluated.
シグナルワード
Warning
危険有害性情報
危険有害性の分類
Eye Irrit. 2 - Skin Irrit. 2
保管分類コード
11 - Combustible Solids
WGK
WGK 3
個人用保護具 (PPE)
dust mask type N95 (US), Eyeshields, Gloves
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
247871-BULK:
247871-25G:
247871-INTR:
247871-100G:
247871-VAR:
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Keishiro Nagoshi et al.
Journal of the American Society for Mass Spectrometry, 29(7), 1473-1483 (2018-04-21)
Radical-driven dissociation (RDD) of hydrogen-deficient peptide ions [M - H + H]·+ has been examined using matrix-assisted laser dissociation/ionization in-source decay mass spectrometry (MALDI-ISD MS) with the hydrogen-abstracting matrices 4-nitro-1-naphthol (4,1-NNL) and 5-nitrosalicylic acid (5-NSA). The preferential fragment ions observed in the ISD spectra
Sookjin Kang et al.
Free radical biology & medicine, 108, 715-724 (2017-05-06)
Mesalazine (5-aminosalicylic acid, 5-ASA), a currently used drug for anti-inflammatory bowel disease, is easily oxidized by HOCl, a strong oxidant generated in gut inflammation, to produce electrophilic quinones. We investigated whether this chemical feature has an implication in the anti-inflammatory
M Zhou et al.
Biochemistry, 38(9), 2636-2646 (1999-03-03)
Pyridoxal 5'-phosphate (PLP) binds tightly to bovine low Mr protein tyrosine phosphatase (BPTP), but it is a very poor substrate for the enzyme. The structural basis of this tight binding of PLP is examined here by a variety of methods.
MALDI mass spectrometry imaging analysis of pituitary adenomas for near-real-time tumor delineation.
David Calligaris et al.
Proceedings of the National Academy of Sciences of the United States of America, 112(32), 9978-9983 (2015-07-29)
We present a proof of concept study designed to support the clinical development of mass spectrometry imaging (MSI) for the detection of pituitary tumors during surgery. We analyzed by matrix-assisted laser desorption/ionization (MALDI) MSI six nonpathological (NP) human pituitary glands
Timotej Strmeň et al.
Rapid communications in mass spectrometry : RCM, 34(10), e8722-e8722 (2020-01-09)
Hyphenation of atmospheric pressure chemical ionization (APCI) mass spectrometry with capillary and micro high-performance liquid chromatography (HPLC) is attractive for many applications, but reliable ion sources dedicated to these conditions are still missing. There are a number of aspects to
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