444286

(R)-(+)-α-Hydroxy-γ-butyrolactone

95%, optical purity ee: 98% (GLC)

• 別名: (R)-4,5-Dihydro-3-hydroxy-2(3H)-furanone
• 実験式（ヒル表記法）: C₄H₆O₃
• CAS番号: 56881-90-4
• 分子量: 102.09
• Beilstein: 80588
• MDL番号: MFCD00211246
• UNSPSCコード: 12352005
• PubChem Substance ID: 24868111
• NACRES: NA.22

特性

• 品質水準: 100
• アッセイ: 95%
• 形状: liquid
• 光学活性: [α]23/D +66°, c = 1.15 in chloroform
• 光学純度: ee: 98% (GLC)
• 屈折率: n20/D 1.467 (lit.)
• bp: 133 °C/10 mmHg (lit.)
• 密度: 1.309 g/mL at 25 °C (lit.)
• 官能基: ester; hydroxyl
• SMILES記法: O[C@@H]1CCOC1=O
• InChI: 1S/C4H6O3/c5-3-1-2-7-4(3)6/h3,5H,1-2H2/t3-/m1/s1
• InChI Key: FWIBCWKHNZBDLS-GSVOUGTGSA-N

詳細

アプリケーション

(R)-(+)-α-Hydroxy-γ-butyrolactone can be used as a starting material to synthesize:

• δ-Azaproline by reacting with benzyloxycarbonyl aminophthalimide via Mitsunobu reactions.
• Homochiral (R)-2,4-dihydroxybutyramide seco-pseudonucleoside reagents.
• Botryolide B via esterification and ring-closing metathesis reaction.
• Pregnane derivatives containing γ-butyrolactones as potential glucocorticoid agonists.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves