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品質水準
アッセイ
97%
形状
powder
mp
318 °C (dec.) (lit.)
SMILES記法
CC1=CC(=O)NC(=O)N1
InChI
1S/C5H6N2O2/c1-3-2-4(8)7-5(9)6-3/h2H,1H3,(H2,6,7,8,9)
InChI Key
SHVCSCWHWMSGTE-UHFFFAOYSA-N
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試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
D115207-BULK:
D115207-5G:
D115207-100G:
D115207-VAR:
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Adrian Häberli et al.
Nucleosides, nucleotides & nucleic acids, 22(5-8), 1187-1189 (2003-10-21)
We synthesized pyrrolidino-C-nucleosides, incorporated them into oligodeoxynucleotides and investigated their pairing properties. The thermal duplex and triplex stabilities were measured. While triplex formation is destabilized in the case of pyrrolidino-pseudo-U and -T, pyrrolidino-pseudo-iso-C leads to an increase of the Tm
H Eshtiagh-Hosseini et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 78(5), 1392-1396 (2011-02-18)
This paper reports the hydrothermal synthesis, experimental and theoretical studies of a novel cocrystal compound in the 2:1 stoichiometric ratio of 6-methyluracil (6mu) and dipicolinic acid (pydcH(2)) formulated as [6mu](2)[pydcH(2)] (1), for the first time. DFT calculations were performed to
Zhiqiang Guo et al.
Bioorganic & medicinal chemistry letters, 13(19), 3311-3315 (2003-09-03)
The novel synthesis and SAR studies of 6-methyluracils as human GnRH receptor antagonists are discussed. Introduction of a small methyl substituent at the beta-position from N3 of the uracil improved the GnRH binding potency by 5- to 10-fold. The best
Effect of tetraalkylammonium derivatives of 6-methyluracil on the endplate potentials of muscles of different functional types.
I V Kovyazina et al.
Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections, 399, 458-460 (2005-02-19)
Fabio C Tucci et al.
Bioorganic & medicinal chemistry letters, 13(19), 3317-3322 (2003-09-03)
A new class of small molecule GnRH antagonists, the 1-arylmethyl-3-(1-methyl-2-amino)ethyl-5-aryl-6-methyluracils, was designed and a novel stereoselective synthesis for these compounds was developed. The stereochemical integrities of key intermediates (S)-6 and (R)-6 were confirmed by a combination of X-ray crystallography and
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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