P57204

ピリダジン

98%

• 別名: 1,2-Diazabenzene, 1,2-Diazine, o-Diazine
• 実験式（ヒル表記法）: C₄H₄N₂
• CAS番号: 289-80-5
• 分子量: 80.09
• Beilstein: 103906
• EC Number: 206-025-5
• MDL番号: MFCD00006463
• UNSPSCコード: 12352100
• PubChem Substance ID: 24898697
• NACRES: NA.22

特性

• 品質水準: 100
• アッセイ: 98%
• 屈折率: n20/D 1.524 (lit.)
• bp: 208 °C (lit.)
• mp: −8 °C (lit.)
• 密度: 1.103 g/mL at 25 °C (lit.)
• SMILES記法: c1ccnnc1
• InChI: 1S/C4H4N2/c1-2-4-6-5-3-1/h1-4H
• InChI Key: PBMFSQRYOILNGV-UHFFFAOYSA-N

詳細

詳細

Pyridazine is a mono-basic 1,2-diazine compound, which is commonly prepared by the reaction of 1,4-dicarbonyls with hydrazines. Pyridazine ring is found in many herbicides like credazine, pyridatol and many pharmaceutical drugs like cefozopran, olaparib, talazoparib, and cadralazine.

アプリケーション

Pyridazine can be used:

• As a building block to synthesize N-phenyl-4-pyrazolo[1,5-b]pyridazin-3-yl-pyrimidin-2-amine derivatives as GSK-3 inhibitors.
• As a starting material in the synthesis of pharmacologically important pyrrolo[1,2-b]pyridazine derivatives.
• To prepare 1-(6-ethoxy-6-oxohexyl)pyridazin-1-ium bromide and 1-(2-bromoacetyl) pyridazinium bromide ionic liquids as corrosion inhibitors of steel under acidic conditions.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 3
• 引火点(°F): 185.0 °F - closed cup
• 引火点(℃): 85 °C - closed cup
• 個人用保護具 (PPE): Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)