QBD10201

Biotin-dPEG^®₃-MAL

• 別名: Polyethylene glycol
• 実験式（ヒル表記法）: C₂₇H₄₃N₅O₈S
• 分子量: 597.72
• UNSPSCコード: 51171641
• PubChem Substance ID: 329823891
• NACRES: NA.22

特性

• アッセイ: >90%
• フォーム: solid or viscous liquid
• 反応適合性: reagent type: cross-linking reagent; reaction type: Biotinylations; reactivity: thiol reactive; reagent type: linker
• ポリマー構造: shape: linear; functionality: monofunctional
• 輸送温度: ambient
• 保管温度: −20°C
• SMILES記法: O=C(NCCCOCCOCCOCCCNC(CCCCC1C2NC(NC2CS1)=O)=O)CCN3C(C=CC3=O)=O
• InChI: 1S/C27H43N5O8S/c33-22(6-2-1-5-21-26-20(19-41-21)30-27(37)31-26)28-10-3-13-38-15-17-40-18-16-39-14-4-11-29-23(34)9-12-32-24(35)7-8-25(32)36/h7-8,20-21,26H,1-6,9-19H2,(H,28,33)(H,29,34)(H2,30,31,37)
• InChI Key: QCEXTKIIGXBNCN-UHFFFAOYSA-N

詳細

アプリケーション

Biotin-dPEG^®₃-MAL can be used as a cross-linking reagent in biotinylation reaction.

特徴および利点

Biotin-dPEG^®₃-MAL takes advantage of the well-known, specific Michael reaction between a maleimide group and a free sulfhydryl to allow site-specific biotin labeling of molecules in aqueous media within the pH range of 6.5 – 7.5. The single molecular weight dPEG^® spacer (24.9 Å) provide precise spacing between the biotin moiety and the labeled molecule. The dPEG^® spacer imparts water solubility to the labeled molecule while reducing immunogenicity, aggregation, and precipitation of labeled biomolecules or other labeled compounds.

法的情報

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable