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安全性情報

850320P

Avanti

09:0 PC

1,2-dinonanoyl-sn-glycero-3-phosphocholine, powder

別名:

PC(9:0/9:0)

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About This Item

実験式（ヒル表記法）:
C26H52NO8P
CAS番号:
27869-45-0
分子量:
537.67
UNSPSCコード:
51191904
NACRES:
NA.25

アッセイ

>99% (TLC)

形状

powder

包装

pkg of 1 × 25 mg (850320P-25mg)

メーカー／製品名

Avanti Research™ - A Croda Brand 850320P

脂質タイプ

cardiolipins
phospholipids

輸送温度

dry ice

保管温度

−20°C

SMILES記法

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCC)=O)COC(CCCCCCCC)=O)=O

InChI

1S/C26H52NO8P/c1-6-8-10-12-14-16-18-25(28)32-22-24(35-26(29)19-17-15-13-11-9-7-2)23-34-36(30,31)33-21-20-27(3,4)5/h24H,6-23H2,1-5H3/t24-/m1/s1

InChI Key

CKGVBFQDYSPMSY-XMMPIXPASA-N

詳細

Phosphatidylcholines (PCs) are amphipathic molecules, which accounts for approximately 40−50% of the total cellular phospholipids. PCs are mainly located on the outer leaflets of the biological membrane bilayer.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

アプリケーション

09:0 PC (1,2-dinonanoyl-sn-glycero-3-phosphocholine) may be used:
  • as an internal standard for phospholipid extraction from renal tissues using liquid chromatography coupled to electrospray ionization tandem mass spectrometry
  • as a supplement in sample mixture as internal standard for liquid-liquid extraction and to spike the samples in order to determine lipid extract from fibroblasts by high-performance liquid chromatography/electrospray ionization tandem mass spectrometry (HPLC/ESI-MS/MS)
  • an internal standard to spike frozen aliquots of plas ma in liquid chromatography with tandem mass spectrometry (LC-MS-MS)

生物化学的／生理学的作用

Phosphatidylcholine (PC) may participate in the signaling of neuronal differentiation.

包装

5 mL Clear Glass Sealed Ampule (850320P-25mg)

法的情報

Avanti Research is a trademark of Avanti Polar Lipids, LLC

保管分類コード

10 - Combustible liquids

WGK

WGK 3

引火点(°F)

Not applicable

引火点(℃)

Not applicable

適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

850320P-25MG:
850320P-VAR:
850320P-BULK:

試験成績書（COA）

製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Maria Philippova et al.
Free radical biology & medicine, 144, 167-175 (2019-05-30)
Circulating oxidized phospholipids are increasingly recognized as biomarkers of atherosclerosis. Clinical association studies have been mainly performed using an immune assay based on monoclonal antibody E06, which recognizes a variety of molecular species of oxidized phosphatidylcholine (OxPC) in lipoproteins, cell
Florian Gruber et al.
Journal of lipid research, 53(6), 1232-1242 (2012-03-15)
Oxidized phospholipids (OxPLs) are increasingly recognized as signaling mediators that are not only markers of oxidative stress but are also "makers" of pathology relevant to disease pathogenesis. Understanding the biological role of individual molecular species of OxPLs requires the knowledge
Zahra Solati et al.
PloS one, 13(4), e0195172-e0195172 (2018-04-24)
The aim of this study was to determine the individual oxidized phosphatidylcholine (OxPC) molecules generated during renal ischemia/ reperfusion (I/R) injury. Kidney ischemia was induced in male Sprague-Dawley rats by clamping the left renal pedicle for 45 min followed by
Luciana Paoletti et al.
IUBMB life, 63(9), 714-720 (2011-08-06)
Neuronal differentiation is characterized by neuritogenesis and neurite outgrowth, processes, which are critically dependent on membrane biosynthesis, and therefore, on the expression and regulation of enzymes involved in phospholipid biosynthesis. During the last decade a great effort was made to
Jelske N van der Veen et al.
Biochimica et biophysica acta. Biomembranes, 1859(9 Pt B), 1558-1572 (2017-04-16)
Phosphatidylcholine (PC) and phosphatidylethanolamine (PE) are the most abundant phospholipids in all mammalian cell membranes. In the 1950s, Eugene Kennedy and co-workers performed groundbreaking research that established the general outline of many of the pathways of phospholipid biosynthesis. In recent

資料

Critical Micelle Concentrations (CMCs) - Avanti® Polar Lipids

The critical micelle concentration (CMC) can be approximately defined as the lipid monomer concentration at which appreciable amounts (>5% of total) of micellar aggregates first begin to appear in the equilibrium: nM1<=>Mn

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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