860535P

Glucosyl(β) Sphingosine (d18:1)

Avanti Research^™ - A Croda Brand

• 別名: D-glucosyl-β1-1′-D-erythro-sphingosine, Glucosylsphingosine
• 実験式（ヒル表記法）: C₂₄H₄₇NO₇
• CAS番号: 52050-17-6
• 分子量: 461.63
• MDL番号: MFCD07374303
• UNSPSCコード: 12352211
• NACRES: NA.25

特性

• フォーム: powder
• 包装: pkg of 1 × 25 mg (860535P-25mg); pkg of 1 × 5 mg (860535P-5mg); pkg of 1 × 50 mg (860535P-50mg)
• メーカー／製品名: Avanti Research^™ - A Croda Brand
• 脂質タイプ: sphingolipids
• 輸送温度: dry ice
• 保管温度: −20°C
• SMILES記法: [H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@](N)([H])CO[C@H](O1)[C@H](O)[C@@H](O)[C@@H]([C@H]1CO)O
• InChI: 1S/C24H47NO7/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19(27)18(25)17-31-24-23(30)22(29)21(28)20(16-26)32-24/h14-15,18-24,26-30H,2-13,16-17,25H2,1H3/b15-14+/t18?,19-,20-,21-,22+,23+,24-/m1/s1
• InChI Key: HHJTWTPUPVQKNA-SKXACSAKSA-N

詳細

詳細

Glucosyl sphingosine is a lyso derivative of glucosylceramide (GlcCer).

アプリケーション

Glucosyl(β) Sphingosine (d18:1) or D-glucosyl-β1-1′-D-erythro-sphingosine may be used:

• to screen lipids that rapidly and reversibly alter transepithelial electrical resistance (TER) or tight junction (TJ) permeability in epithelial tissue
• as a standard for the quantification of glucosyl sphingosine in Gaucher patients using liquid chromatography electrospray ionization tandem mass spectrometric (LC/ESI-MS/MS)
• as an internal standard for the quantification of lysoglucosylceramide in plasma for Gaucher disease using liquid chromatography with tandem mass spectrometry (LC-MS/MS)

生物化学的／生理学的作用

Glucosyl sphingosine is a potential biomarker for Gaucher′s disease. It modulates Ca²⁺ release in the brain microsomes.

包装

5 mL Amber Glass Screw Cap Vial (860535P-25mg)

5 mL Amber Glass Screw Cap Vial (860535P-50mg)

5 mL Amber Glass Screw Cap Vial (860535P-5mg)

法的情報

Avanti Research is a trademark of Avanti Polar Lipids, LLC

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable