D-088

N-Desmethylcyclobenzaprine hydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant^®

• 実験式（ヒル表記法）: C₁₉H₁₉N · HCl
• CAS番号: 438-59-5
• 分子量: 297.82
• MDL番号: MFCD01731061
• UNSPSCコード: 41116107
• PubChem Substance ID: 329798646
• NACRES: NA.24

特性

• グレード: certified reference material
• 品質水準: 300
• 形状: liquid
• 特徴: (Snap-N-Spike^®)
• 包装: ampule of 1 mL
• メーカー／製品名: Cerilliant^®
• 濃度: 1.0 mg/mL in methanol (as free base)
• テクニック: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• アプリケーション: clinical testing
• フォーマット: single component solution
• 保管温度: −20°C
• SMILES記法: CNCCC=C1C2=C(C=CC=C2)C=CC3=C1C=CC=C3.Cl
• InChI: 1S/C19H19N.ClH/c1-20-14-6-11-19-17-9-4-2-7-15(17)12-13-16-8-3-5-10-18(16)19;/h2-5,7-13,20H,6,14H2,1H3;1H
• InChI Key: UZMPCPFDZYTEJG-UHFFFAOYSA-N

詳細

詳細

A certified Snap-N-Spike^® Solution suitable for cyclobenzaprine testing methods by GC/MS or LC/MS for applications in pain prescription monitoring, forensic analysis, urine drug testing, or clinical toxicology. Also known as norcyclobenzaprine, N-desmethylcyclobenzaprine is the major urinary metabolite of the skeletal muscle relaxant cyclobenzaprine. Cyclobenzaprine, sold under trade names Flexeril^®, Fexmid^®, and Amrix^®, is used to relieve skeletal muscle spasms and associated pain from acute musculoskeletal conditions.

アプリケーション

• Formation of Mammalian Metabolites of Cyclobenzaprine: Research demonstrated that the fungus Cunninghamella elegans could produce mammalian metabolites of cyclobenzaprine, including N-Desmethylcyclobenzaprine. This study highlights the potential use of microbial models in pharmacokinetic studies to simulate and study drug metabolism pathways, providing a cost-effective and simpler alternative to traditional in vivo metabolic studies (Zhang et al., 1996).

法的情報

Amrix is a registered trademark of Ivax International GMBH LLC

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Fexmid is a registered trademark of Shionogi Inc.

Flexeril is a registered trademark of ALZA Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS02,GHS06,GHS08,GHS09
• シグナルワード: Danger
• 危険有害性情報: H225,H301 + H311 + H331,H370,H411
• 注意書き: P210 - P273 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• 危険有害性の分類: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Flam. Liq. 2 - STOT SE 1
• ターゲットの組織: Eyes
• 保管分類コード: 3 - Flammable liquids
• WGK: WGK 1
• 引火点(°F): 49.5 °F
• 引火点(℃): 9.7 °C