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Merck
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安全性情報

I-033

Supelco

IGF-1 solution

100 μg/mL (2% Acetic acid, 2mM Methionine, pH as is), certified reference material, pkg of 1 mL (Cryoules), Cerilliant®

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About This Item

CAS番号:
UNSPSCコード:
41116107
NACRES:
NA.24

グレード

certified reference material

品質水準

形状

liquid

分子量

7654.74 Da

特徴

Snap-N-Spike®/Snap-N-Shoot®

包装

pkg of 1 mL (Cryoules)

メーカー/製品名

Cerilliant®

濃度

100 μg/mL (2% Acetic acid, 2mM Methionine, pH as is)

テクニック

liquid chromatography (LC): suitable

アプリケーション

clinical testing

フォーマット

single component solution

輸送温度

dry ice

保管温度

−20°C

詳細

Insulin-like growth factor 1 (IGF-1), also called somatomedin C, is a protein hormone that plays an important role in childhood growth and continues to have anabolic effects in adults. Measuring IGF-1 levels is used to test for growth hormone deficiency and excess in acromegaly and gigantism. This certified Snap-N-Spike® solution of the fully-intact IGF-1 protein is suitable for use as starting material for calibrators and controls in IGF-1 LC/MS testing applications.
The quantitative analysis of IGF-I has played a crucial role in diagnosing and treating human growth disorders ever since its serum measurement became widely accessible. IGF-1 serves as a biomarker for growth hormone (GH) activity. This product is a certified reference material containing a human insulin solution. The insulin contained in this product is derived from recombinant sources of human origin. It is prepared in line with the ISO guidelines and satisfies the criteria for both certified reference material and primary standard categories. It is traceable to higher-order standards through an unbroken chain of comparisons. Furthermore, it is created from a pure substance in an aqueous solvent solution, which constitutes a primary standard.

アプリケーション

IGF-1 solution is suitable for the in vitro identification, calibration, and quantification of the analyte(s) in analytical and R&D applications.

特徴および利点

  • The content of IGF-1 is determined using quantitative amino acid analysis (AAA) and HPLC/UV/MS.
  • No adjustments required before using this standard.
  • It has been prepared and certified in accordance with the ISO 17034, ISO/IEC 17025, and ISO 9001 standards.
  • All raw materials used in the product have undergone comprehensive identification and characterization processes utilizing various analytical techniques.
  • Long-term stability has been evaluated for storage in freezer conditions (-10 °C to -25 °C).

調製ノート

  • Prior to use, thaw the product either in the refrigerator or at room temperature, and ensure thorough mixing.
  • Do not attempt to refreeze the product once thawed.
  • Thawed product can be stored in a refrigerated environment for up to 8 weeks.
  • When using the product, it is recommended that users quantitatively transfer the desired volume, following established good laboratory practices. This can be done either to spike it into a matrix or to dilute it to the desired concentration.

その他情報

This product′s purpose is for testing. THIS PRODUCT IS NOT INTENDED FOR HUMAN OR THERAPEUTIC USE. Refer to the safety data sheet for specific details regarding any possible hazards and necessary precautions.

法的情報

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

保管分類コード

12 - Non Combustible Liquids

WGK

nwg

引火点(°F)

Not applicable

引火点(℃)

Not applicable


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

労働安全衛生法名称等を表示すべき危険物及び有害物

名称等を表示すべき危険物及び有害物

労働安全衛生法名称等を通知すべき危険物及び有害物

名称等を通知すべき危険物及び有害物

Jan Code

I-033-1ML:4548173355436


試験成績書(COA)

製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Clinical utility of insulin-like growth factor 1 and 2; determination by high resolution mass spectrometry
Bystrom C, et al.
PLoS ONE, 7(9) (2012)
Discordance between mass spectrometry and immunometric IGF-1 assay in pituitary disease: a prospective study
Bonert V, et al.
Pituitary, 21(1) (2018)
Clinical utility of insulin-like growth factor 1 and 2; determination by high resolution mass spectrometry
Bystrom C, et al.
Testing, 7(9) (2012)
Narrow mass extraction of time-of-flight data for quantitative analysis of proteins: determination of insulin-like growth factor-1
Bystrom CE, et al.
Analytical Chemistry, 83(23) (2011)

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