M-160

(±)-4-Methylephedrine-D₃ hydrochloride solution

100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant^®

• 別名: Deuterated 4-methylephedrine hydrochloride solution
• 実験式（ヒル表記法）: C₁₁H₁₄D₃NO · HCl
• 分子量: 218.74
• EC Number: 200-659-6
• UNSPSCコード: 41116107
• NACRES: NA.24

特性

• グレード: certified reference material
• 品質水準: 300
• 形状: liquid
• 特徴: (Snap-N-Spike^®)
• 包装: ampule of 1 mL
• メーカー／製品名: Cerilliant^®
• 濃度: 100 μg/mL in methanol (as free base)
• テクニック: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• アプリケーション: forensics and toxicology
• フォーマット: single component solution
• 保管温度: −20°C
• SMILES記法: CC(NC([2H])([2H])[2H])C(O)C1=CC=C(C)C=C1.Cl
• InChI: 1S/C11H17NO.ClH/c1-8-4-6-10(7-5-8)11(13)9(2)12-3;/h4-7,9,11-13H,1-3H3;1H/i3D3;
• InChI Key: DDFKODAFZRBBOK-FJCVKDQNSA-N

詳細

詳細

A bath salt cathinone analog and primary urinary metabolite of mephedrone. Mephedrone, also known as 4-methylmethcathinone, is a synthetic cathinone and stimulant widely found in numerous bath salt blends across the US, Europe, and Asia. This certified Snap-N-Spike^® solution is suitable as an internal standard for quantitation of (±)-4-Methylephedrine by LC/MS or GC/MS for applications in urine drug testing, clinical toxicology, or forensic testing.

アプリケーション

• (±)-4-Methylephedrine-D₃ hydrochloride as an analytical standard: This compound is extensively used as a stable isotope-labeled standard in mass spectrometry, enhancing the accuracy and precision of analytical methods for detecting and quantifying ephedrine and its derivatives in complex biological matrices. Its role is crucial in doping control, forensic analysis, and therapeutic drug monitoring (Deshpande et al., 2024).


• Pharmaceutical research applications: In pharmaceutical research, (±)-4-Methylephedrine-D₃ hydrochloride is employed to study the pharmacokinetics and metabolism of ephedrine-based drugs. Its deuterated form provides an internal standard that is vital for achieving reliable quantification in bioanalytical studies, particularly in the development of new therapeutic agents.


• Enhancing mass spectrometry techniques: The use of (±)-4-Methylephedrine-D₃ hydrochloride in mass spectrometry significantly improves the method′s sensitivity and specificity. This is especially important in the field of toxicology and pharmacology, where precise measurements are essential for understanding drug behavior and ensuring patient safety.


• Studying chiral drug interactions: As a chiral compound, (±)-4-Methylephedrine-D₃ hydrochloride aids in the research of stereoselective drug interactions, which are crucial for developing safer and more effective pharmaceutical formulations. This application helps in distinguishing the different enantiomers of chiral drugs and their distinct pharmacological effects.


• Development of bioanalytical methods: This high-purity deuterated compound is used for developing and validating robust bioanalytical methods in biochemistry studies. It ensures that the analytical methods used in clinical and pharmacological research are both accurate and reproducible, facilitating the assessment of drug efficacy and safety in biological systems.

法的情報

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS02,GHS06,GHS08
• シグナルワード: Danger
• 危険有害性情報: H225,H301 + H311 + H331,H370
• 注意書き: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• 危険有害性の分類: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• ターゲットの組織: Eyes
• 保管分類コード: 3 - Flammable liquids
• WGK: WGK 1
• 引火点(°F): 49.5 °F
• 引火点(℃): 9.7 °C